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Attack of the kinases: JNK signaling in metabolism.

Fernández-González(I),Vattathara(JJ),Davis... Am J Physiol Regul Integr C... 2026-04-01

...Jun N-terminal kinase (JNK) have gained wide attention as key players that integrate nutrient-, hormone-, and inflammati...

SOCS2 deficiency drives sex-specific remodeling of mineralized tissues.

Toyama(RV),Colares(JP),Refaxo(NA),de Arrud... Bone 2026-06-00

...Jun N-terminal kinase activity in SOCS2-/- males, sex-divergent Pparγ, Il6, and Runx2 expression, and unchanged Rankl/Op...

Environmental PET-microplastic exposure and risk of non-alcoholic fatty liver...

Yuan(Y),Lin(C),Zhang(T),Song(C),Sun(Y),Tan... Naunyn Schmiedebergs Arch P... 2026-05-00

...JUN, PFKFB3, PIM1, and PPARA. The resulting diagnostic model achieving a maximum Area Under the Curve (AUC) of 0.94 in t...

Jaceidin Suppresses Melanoma Metastasis by Modulating ERK, JNK Pathways and E...

Shieu(MK),Yang(HJ),Lin(CC),Kao(MY),Ho(HY),... J Cell Mol Med 2026-02-00

...Jun N-terminal kinase, as well as suppressing proteins associated with epithelial-mesenchymal transition. Furthermore, j...

Quercetin Suppresses Inflammation and Extracellular Matrix Degradation in Kne...

Yao(J),Li(J),Zhang(Y),Guo(P),Li(J),Sun(S) Chem Biol Drug Des 2026-02-00

...Jun N-terminal kinase (JNK) pathway. E2F2 bound the SFRP5 promoter and inhibited its transcription, whereas SFRP5 overex...

Single-cell transcriptomics reveals phenotypic and functional alterations of ...

Zhang(H),Cao(Y),Yang(L),Liu(B),Guan(J),Wan... Tuberculosis (Edinb) 2026-03-00

...JUN and ribosomal genes, consistent with enhanced differentiation. EPC_DTB and EPC_TB interacted with macrophages, dendr...

CD146 + interstitial cells contribute to the dystrophic skeletal muscle pheno...

Mierzejewski(B),Michalska(Z),Kulma(D),Bos(... Sci Rep 2026-02-24

...Jun, and c-Fos pathways activity as contributors to these pathological changes. These findings suggest that CD146 + cell...

From hPSCs to MSCs: differentiation strategies, pathways, and the emergence o...

Liang(S),Qian(Z),Wang(Y),Huangfu(J),Ren(W) Cell Mol Biol Lett 2026-02-24

...JUN, JUND, FOSL1, FOSL2) and the associated regulatory targets (FN1 and COL1A1) emerged as recurrent hubs in mesenchymal...

Therapeutic effect and anti-inflammatory mechanism of modified Shoutai pills ...

Junwei(LI),Xinyue(L),Xuan(M),Hongliang(X),... J Tradit Chin Med 2026-02-00

...Jun N-terminal kinase 1, p38, and tumor necrosis factor-α. In this study, we demonstrated that MSTP effectively prevente...

Mocetinostat (MGCD0103) induced autophagy in SKBR-3 breast cancer cells by re...

Çakir(HK),Eroglu(O) J Investig Med 2026-02-25

...JUN, (Cellular Jun proto-oncogene transcription) and the upregulation of P53 and ATG5 (Autophagy-Related Genes) thereby ...

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