...KRAS) G12C mutation.
...KRAS alterations, treated with MEKi therapies between 2022-2024. Ten patients had KRAS G12R (34.5%), ten G12D (34.5%), a...
...KRAS, and IDH2 were identified, demonstrating the potential for mosaic variant detection to inform treatment strategies....
...KRAS mutations that drive many cancers. By leveraging natural competence and horizontal gene transfer, in combination wi...
...KRASG12D and KRASG12C mutant PDAC cells resistant to allele-specific KRAS inhibitors. Oral administration of ADT-030 sig...
...KRAS co-mutations regrew after RMC-6272 treatment, which was prevented by the addition of the RAS(ON) multi-selective in...
...KRAS co-mutant non-small cell lung cancer (NSCLC), Mtp53 enhances tumor immunogenicity and improves response to immune c...
...KRAS as a synthetic lethal gene pair in TNBC. Functional experiments demonstrated that the knockdown of KIF22 in KRAS-mu...
...Kras-driven, p53-deleted (KPC) mouse model of pancreatic ductal adenocarcinoma. This well-established clinically relevan...
...KRAS and KEAP1 mutations, creating a dependency on glutaminase (GLS)-mediated glutaminolysis for survival and growth. Al...
山东省济南市章丘区文博路2号
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