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Dietary titanium dioxide particles (E171) promote colitis-associated colorectal…

Wang(P),Zhong(Y),Liu(J),Gao(L),Long(T),Li(Z) Chin J Nat Med 2026-02-00

...Lcn2, S100a11, Cxcl2, and interleukin-1α (Il-1α). E171 also increased the expression of S100A8, S100A9, NOD-like recepto...

Protective Effects of Jiawei Baihu Tang in Kawasaki Disease: Omics Analysis and…

Ma(J),Song(X),Li(X),Tang(Y),Lv(H),Chen(Y),Ca… Cardiovasc Drugs Ther 2026-08-00

...LCN2/MMP9) axis in vascular remodeling. Histopathological analysis, multiplex immunofluorescence, data-independent acqui...

Clinical and molecular correlates of digitally quantified anthracosis in lung t…

Fung(LC),Joseph(B),Ofori-Amanfo(K),Lo(T),Wan… J Pathol Clin Res 2026-07-00

...LCN2, SPA17), the activation of inflammatory response and cytokine gene sets, and suppression of the antigen processing ...

TNF receptor-associated factor 6 sensitizes prostate cancer cells to CD8+ T cel…

Shi(Y),Lv(Z),Zhang(X),Jiang(A),Wu(C),Wang(C)… Int J Biol Macromol 2026-07-20

...LCN2) for proteasomal degradation. The anti-tumor effects of TRAF6 overexpression were reversed upon LCN2 restoration. F...

Integrative multi-omics analysis identifies FAM3D as a prognostic tumor suppres…

Chen(Y),Hong(Y),Wei(D),Fan(L),Tao(D),Zhang(R… Funct Integr Genomics 2026-07-21

...LCN2. FAM3D is a potential tumor suppressor and prognostic biomarker in CC, whose expression is partially regulated by p...

The protective effect of Lcn2 activation on salivary gland injury in sialadenit…

Feng(G),Li(J),Huang(L),Xia(Y),Yang(J),Cheng(… Int Immunopharmacol 2026-08-01

...Lcn2 knockdown. To further assess the functional role of Lcn2, mice were administered adeno-associated virus 2 (AAV2) to...

Tumor-derived exosomes carry LCN2 to block Nedd4-1-mediated SR-BI ubiquitinatio…

Yang(L),Chang(Y),Gan(G),Deng(W),Li(S) Funct Integr Genomics 2026-01-06

...LCN2 being highly expressed in HCC exosomes. In vitro experiments showed that LCN2 was significantly enriched in exosome...

Refined Jianpi Huayu Jiedu Decoction Attenuates TAM-Induced Spasmolytic Polypep…

Fang(C),Zhang(S),He(P),Lai(Y),Luo(R),Zhang(Y… Pharmaceuticals (Basel) 2026-04-24

...LCN2-related epithelial stress and mitochondrial regulatory networks. Functional validation further demonstrated that LC...

LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-aut…

Chen(SX),Qi(X),Zheng(XT),Bi(ZM),Zhang(Y),Wan… Apoptosis 2026-03-15

...LCN2) played the most important role in the development of ALI, and mechanistic studies confirmed that LCN2 aggravated s...

Vps35 p. D620N causes Lrrk2 kinase hyperactivity, chronic microglial activation…

Deng(IB),Bu(M),Follett(J),Sharp(R),Mamais(A)… bioRxiv 2026-03-11

...Lcn2), were significantly upregulated, and those measures were complimented by immunohistochemistry and quantitative PCR...

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