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Functional Characteristics and Stress Tolerance of Microbiota in Botswana's Tra…

Semumu(T),Zhou(N),Lebani(K),Ndlovu(T),Wale(K… Curr Microbiol 2026-04-17

...ME1-B1), B. cereus (GT1-B1) and B. zhangzhouensis were able to withstand baking associated stresses better than all othe...

Malic enzyme 1 contributes to tumorigenesis and lenvatinib resistance in hepato…

Wu(D),Xu(H),Guo(Y),Lu(L),Han(D),Chen(L),Lei(… Cell Death Dis 2026-03-25

...ME1 promoted HCC cell viability in vitro. Consistently, hepatocyte-specific Me1 knockout (Me1HKO) mice treated with diet...

Proteomics-Based Study of Potential Emphysema Biomarkers Reveals Systemic Redox…

Salai(G),Novak(R),Hrkač(S),Pustka(V),Potěšil… Diagnostics (Basel) 2026-03-21

...ME1) being the only DEP in the CE vs. CN contrast. Proteins such as BMP1, ADAMTSL-2, -4 and IGFBP4, -5, 6 were identifie...

Unraveling cellular longevity pathways in poultry under heat stress: functional…

Shamana(K),Edwin(R),Jaishree(SP),Prashanth(D… In Silico Pharmacol None

...ME1, FADS2, ALDH1L2, and DHCR7 showed significant enhancement post-treatment. There was also a restoration of several do...

Design and synthesis of quinazoline derivatives as novel JMJD3/HDAC dual-target…

Wang(L),Zhang(Y),Chen(K),Liu(Y),Zhang(X),Xu(… RSC Med Chem 2026-07-13

...me1/me2/me3) and H3 acetylation. The therapeutic potential of these JMJD3/HDAC inhibitors was further evaluated in TNBC ...

Deubiquitination of ME1 by OTUD7B promotes aerobic glycolysis of esophageal can…

Guan(L),Li(X),Du(Z),Yuan(Q),Zhou(F),Li(X),Xu… Biochem Pharmacol 2026-08-11

...ME1 to EC growth via aerobic glycolysis remains unclear. This study aimed to investigate the role of ME1 in EC and the u...

A cryptic allosteric pocket shapes isoform-selective inhibition of human malic …

Krinkel(BA),Yosaatmadja(Y),Slayton(MD),Krink… Protein Sci 2026-09-00

...ME1-3), suggesting that selectivity must arise elsewhere than the active site. Here, we define matched kinetic and regul...

Comprehensive Analysis of Malate Accumulation in Peaches in Response to Cold St…

Cai(H),Han(S),Wang(X),Shi(J),Xiong(Z),Zhang(… Food Sci Nutr 2026-01-00

...ME1) showed limited alignment with malate accumulation. In contrast, genes implicated in proton pump and malate transpor...

Inhibition of Methyltransferase DOT1L alleviates anti-tuberculosis drug-induced…

Jinfeng(L),Shengfei(P),Dongxue(W),Yifei(L),Q… Eur J Pharmacol 2026-01-10

...me1), dimethylation (me2) and trimethylation (me3) of histone H3 at lysine 79 (H3K79), despite lacking a SET domain. Bey...

Mult omics reveal the mechanism of solid dispersion of genistein in alleviating…

Liu(D),Guo(H),Yang(Y),He(X),Zhao(X) Poult Sci 2026-04-00

...ME1. The underlying mechanism may involve the inhibition of hepatic triglyceride synthesis, the facilitation of free cho...

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