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Accelerating novel candidate gene discovery in neurogenetic disorders via who...

Alazami(Anas M),Patel(Nisha),Shamseldin(Ha... Cell Rep 2015-09-25

...MYOCD, PDPR, DPH1, NUP107, TMEM92, EPB41L4A, and FAM120AOS). We also encountered instances in which the phenotype depart...

Generation of a Cre knock-in into the Myocardin locus to mark early cardiac a...

Espinoza-Lewis(Ramón A),Wang(Da-Zhi) Genesis 2015-06-23

...Myocd(KI)). We report that the Myocd(KI) allele expresses the Cre enzyme and the EGFP in a manner that recapitulates end...

Gene expression profiling in leiomyosarcomas and undifferentiated pleomorphic...

Villacis(Rolando A R),Silveira(Sara M),Bar... PLoS One 2015-03-09

...MYOCD, SRF and SRC) selected from the gene signature, meta-analysis and functional in silico analysis were further valid...

Phenotypic transition of corpus cavernosum smooth muscle cells subjected to h...

Lv(Bodong),Zhao(Jianfeng),Yang(Fan),Huang(... Cell Tissue Res 2015-09-01

...Myocd expression. In addition, a HIF-1α knockdown effectively reversed the hypoxia-induced CCSMC phenotype, whereas its ...

Progesterone receptor-dependent regulation of genes in the oviducts of female...

Akison(Lisa K),Boden(Michael J),Kennaway(D... Physiol Genomics 2015-10-26

...Myocd, and Actg2) and one upregulated (Agtr2) in PGR null oviducts. Expression of these genes was also assessed in ovidu...

Cardiac gene activation analysis in mammalian non-myoblasic cells by Nkx2-5, ...

Zhou(Lei),Liu(Yu),Lu(Li),Lu(Xinzheng),Dixo... PLoS One 2014-08-26

...Myocd alone or Tbx5+Myocd, Tbx5+Gata4+Myocd activated the fewest genes associated with non-cardiac processes. Conclusive...

Identification of a Klf4-dependent upstream repressor region mediating transc...

Turner(Elizebeth C),Huang(Chien-Ling),Govi... Biochim Biophys Acta 2014-01-02

...Myocd) gene, the master gene regulator of SMC differentiation, have yet to be identified. In this study, we sought to id...

Ten-eleven translocation-2 (TET2) is a master regulator of smooth muscle cell...

Liu(Renjing),Jin(Yu),Tang(Wai Ho),Qin(Ling... Circulation 2014-01-27

...MYOCD) and KLF4, have been identified, a unifying epigenetic mechanism that confers reversible SMC differentiation has n...

Cell division cycle 7 mediates transforming growth factor-β-induced smooth mu...

Shi(Ning),Chen(Shi-You) J Biol Chem 2014-02-21

...Myocd promoter activity. Cdc7 appears to enhance Nkx2.5 binding to Myocd promoter, leading to Myocd activation. Taken to...

Gene expression profiling of HGF/Met activation in neonatal mouse heart.

Gatti(Stefano),Leo(Christian),Gallo(Simona... Transgenic Res 2014-01-06

...MyocD, an activator of cardiac gene expression, and Hdac5, an inhibitor of cardiac growth. These results may unveil a ne...

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