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Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferati...

Liu(Changmei),Teng(Zhao-Qian),Santistevan(... Cell Stem Cell 2010-09-21

...Numblike (Numbl), a known regulator of brain development, by binding to the 3'-UTR of Numbl mRNA and affecting its trans...

NUMBL interacts with TRAF6 and promotes the degradation of TRAF6.

Zhou(Li),Ma(Qi),Shi(Huili),Huo(Keke) Biochem Biophys Res Commun 2010-03-23

...NUMBL interacts with TAB2 and negatively regulates NF-kappaB signaling pathway. Here, we report that NUMBL directly bind...

Norepinephrine transport-mediated gene expression in noradrenergic neurogenesis.

Hu(Yao Fei),Caron(Marc G),Sieber-Blum(Maya... BMC Genomics 2009-09-18

...Numbl. Differentially expressed genes that are likely to contribute to the NETKO phenotype include dopamine-beta-hydroxy...

NUMBL interacts with TAB2 and inhibits TNFalpha and IL-1beta-induced NF-kappa...

Ma(Qi),Zhou(Li),Shi(Huili),Huo(Keke) Cell Signal 2008-09-29

...NUMBL. The interaction was further confirmed in vitro and in vivo. PTB domain of NUMBL and C-terminal region are require...

Mutation and copy number analysis of LNX1 and Numbl in nervous system tumors.

Blom(Tea),Roselli(Annariikka),Tanner(Minna... Cancer Genet Cytogenet 2008-11-04

...Numbl genes. In addition, gene copy numbers of LNX1, Numbl, and KIT in human nervous system tumors were analyzed by chro...

Numb and Numbl are required for maintenance of cadherin-based adhesion and po...

Rasin(Mladen-Roko),Gazula(Valeswara-Rao),B... Nat Neurosci 2007-08-30

...Numbl inactivation in RGCs decreases proper basolateral insertion of cadherins and disrupts adherens junctions and polar...

Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-gl...

Passos Gregorio(Sheila),Gattaz(Wagner F),T... Schizophr Res 2007-02-06

...NUMBL) to schizophrenia in a group of 200 Brazilian patients and 200-paired controls. Also, we replicated the associatio...

The enigma of the numb-Notch relationship during mammalian embryogenesis.

Petersen(Petur H),Tang(Haiyan),Zou(Kaiyong... Dev Neurosci 2006-05-30

...Numblike (Numbl or Nbl), and eliminating Notch signaling in the developing nervous system both lead to premature depleti...

NUMB is a break of WNT-Notch signaling cycle.

Katoh(Masuko),Katoh(Masaru) Int J Mol Med 2006-10-25

...NUMBL), are docking proteins with PTB domain. We searched for the TCF/LEF-binding site within the promoter region of NUM...

Zebrafish Numb homologue: phylogenetic evolution and involvement in regulatio...

Niikura(Yuichi),Tabata(Yoko),Tajima(Atsush... Mech Dev 2006-09-25

...Numbl proteins suggest that znumb is more closely related to Numbl than Numb. znumb mRNA was expressed in a wide variety...

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