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Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder...

Ruderfer(D M),Fanous(A H),Ripke(S),McQuill... Mol Psychiatry 2015-06-05

...PIK3C2A. We create a polygenic risk score that is significantly different between BP and SCZ and show a significant corr...

Discovery and functional assessment of gene variants in the vascular endothel...

Paré-Brunet(Laia),Glubb(Dylan),Evans(Patri... Hum Mutat 2014-08-07

...PIK3C2A, and MAP2K6 could predict 44%, 37%, and 45% of the variance in gene expression, respectively. This is the first ...

Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation...

Iwai(Leo K),Payne(Leo S),Luczynski(Maciej ... Biochem J 2013-11-04

...PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2α) and PLCL2 (phospholipase C-like 2). Bioch...

Gata3 antagonizes cancer progression in Pten-deficient prostates.

Nguyen(Alana H T),Tremblay(Mathieu),Haigh(... Hum Mol Genet 2013-12-31

...Pik3c2a mRNAs, encoding respectively class I and II PI3K subunits. Remarkably, the majority of human prostate tumors sim...

Polymorphisms in AKT3, FIGF, PRKAG3, and TGF-β genes are associated with myof...

Chen(Sirui),An(Jianyong),Lian(Ling),Qu(Luj... Poult Sci 2013-03-05

...PIK3C2A, AKT3, PRKAB2, PRKAG3, VEGFA, RPS6KA2/3, FIGF, and TGF-β1/2/3, were chosen to be genotyped by high-throughput ma...

Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induc...

Schepeler(T),Holm(A),Halvey(P),Nordentoft(... Oncogene 2012-08-21

...PIK3C2A that were directly repressed by several miRNA binding sites as confirmed by luciferase reporter assays in combin...

Altered expression of lipid metabolism and immune response genes in the front...

Lalovic(Aleksandra),Klempan(Tim),Sequeira(... J Affect Disord 2010-03-19

...PIK3C2A) and stearoyl-CoA desaturase (SCD) were consistently down-regulated in all three regions of the frontal cortex o...

Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of...

Koutros(Stella),Schumacher(Fredrick R),Hay... Cancer Res 2010-04-26

...PIK3C2A, PIK3CD, and PIK3R3) and prostate cancer risk in 8,309 cases and 9,286 controls. Odds ratios (OR) and 95% confid...

Gene expression patterns of hippocampus and cerebral cortex of senescence-acc...

Zheng(Yue),Cheng(Xiao-Rui),Zhou(Wen-Xia),Z... Neurosci Lett 2008-10-14

...Pik3c2a), protein metabolism (Ttc3, Amfr, Prr6, Ube2d2), cell growth and development (Ngrn, Anln, Dip3b, Acrbp), nucleic...

Expression profiles are different in carbon ion-irradiated normal human fibro...

Iwakawa(Mayumi),Hamada(Nobuyuki),Imadome(K... Mutat Res 2008-08-20

...PIK3C2A, GNA13, FN1, ANXA1 and IL1RAP), stress response (RAD23B, ATF4 and EIF2AK4) and cell cycle (MYCN, RBBP4 and NEURO...

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