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The p.T216R mutation of the thromboxane A2 receptor disrupts platelet functio...

Denis(K),Heim(V),Fiore(M),Laeufer(P),Eckly... J Thromb Haemost 2026-08-00

...RhoA signaling pathway. Defective aggregation responses were observed when the platelets were stimulated by U46619, arac...

Single-Cell Transcriptomics Identifies a Pivotal Role of SPHK1+ Macrophage-Dr...

Tang(D),Han(Y),Jiang(H),Uzokov(J),Li(F),Wa... Inflammation 2026-04-16

...RhoA-ROCK1 signaling pathway. In vivo studies revealed a 40% reduction in the incidence of AD and significantly reduced ...

WNT5a-Mediated Aberrant Actin Filament Dynamics Drive Cardiac Pathogenic Phen...

Fan(H),Wang(X),Liu(X),Zhao(J),Zhang(Y),Yan... Circulation 2026-06-02

...RhoA (Ras homolog family member A) signaling inactivation was shown to lead to actin depolymerization and inhibition of ...

Regulation of Nucleus Pulposus Cell Phenotype Through RhoA Signaling and Micr...

Bond(G),Kim(MKM),Lisiewski(L),Jacobsen(T),... bioRxiv 2026-04-07

...RhoA with CT04 reduced RhoA activity, decreased actomyosin contractility gene expression, and shifted morphology toward ...

Gastrodin alleviates neuronal damage in epileptic cell models by targeting P2...

Cai(A),Li(Z),Liu(R),Huang(H),Liu(P),Zhang(... PLoS One None

...RhoA/ROCK signaling pathway. In an in vitro epilepsy model induced by kainic acid (KA), Gastrodin intervention significa...

External mechanical force drives axonal cytoskeletal rearrangements.

Swaim(GL),Glomb(OV),Xie(Y),Emerson(C),Li(Z... Curr Biol 2026-05-18

...RhoA, and non-muscle myosin II function in a C. elegans motor neuron axon in response to forces generated by muscle cont...

CD20 tails interact with the 14-3-3/GEF-H1 complex and microtubule network up...

Kläsener(K),Lee(CE),Bender(J),Naumann(A),R... EMBO J 2026-06-00

...RhoA GDP/GTP exchange factor GEF-H1 and the microtubule network, supporting the function of the IgD-BCR nanocluster. Bin...

Single-cell transcriptomics identify mechanical-memory-associated cell states...

Zhao(X),Fan(Y),Yang(J),Gao(H) Breast Cancer Res 2026-04-17

...RHOA, TIMP1, and MMP14. In 3D collagen cultures, matrix stiffening markedly increased RELA and MMP14 expression, while p...

Exosomal lncRNA SILC1 from bicalutamide-activated mesenchymal stem cells prom...

Yu(J),Liang(H),Lu(D),Pham(TH),Mo(Q),Hussei... J Transl Med 2026-04-18

...RHOA expression. Notably, high expression levels of RHOA are associated with increased proliferation, invasion, and enha...

Rho-associated kinase (ROCK)-associated proteins and genes-encoded proteins u...

Zakaria(MA),Rajab(NF),Chua(EW),Zawawi(MRA)... J Egypt Natl Canc Inst 2026-04-20

...RhoABC, ROCK1, ROCK2, and pMLC during LUSC progression via IHC and Western blot assays. Notably, RhoA, RhoB, and pMLC (M...

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