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Electrostatic properties of disordered regions control transcription factor sea…

Sakong(S),Fierz(B),Suter(DM) Nat Commun 2026-02-08

...Sox2 markedly enhances search efficiency compared to the negatively-charged flanking region of Sox17. The involved mecha...

Vitamin D Reprograms Non-Coding RNA Networks to Block Zika Virus in Human Macro…

Ramírez-Mejía(JM),Fernandez(GJ),Urcuqui-Inch… Pathophysiology 2026-02-03

...SOX2-OT and SLC9A3-AS1 may act as molecular sponges, modulating regulatory axes relevant to immune control and viral res...

The human induced pluripotent stem cell line CTGUi-002A was generated from a Pe…

Wu(SL),Li(Y),Dou(T),Wang(W),Zhan(JQ),Lv(YF) Stem Cell Res 2026-04-00

...SOX2, KLF4, and c-MYC. The CTGUi002-A iPSC line retained the TWNK mutations and exhibited characteristic iPSC morphology...

Altered perivascular diffusivity in glioblastoma: integrating DTI-ALPS index wi…

Nath(B),Bobholz(SA),Kim(DC),Lowman(AK),Duenw… J Neurooncol 2026-02-21

...SOX2 positive tumor cells in the perivascular spaces. DTI-ALPS metrics were not independently associated with overall su...

KIF20A inhibits TRIM21-dependent ubiquitination of DHX9 to boost SOX2 stability…

Zhang(Z),Li(Y),Hu(J),Tang(X),Li(Z),Sun(X),Fe… Cell Death Dis 2026-02-11

...SOX2 mRNA stability, leading to upregulation of SOX2, a central regulator of both CSC maintenance and ferroptosis resist...

FATE-MAP predicts teratogenicity and human gastrulation failure modes by integr…

Rufo(J),Qiu(C),Han(D),Baxter(N),Daley(G),Dhi… Nat Commun 2026-02-19

...SOX2 stability, that form orthogonal morphospace axes along which canonically patterned gastruloids systematically vary....

A syngeneic glioblastoma mouse model with mesenchymal hallmarks.

Joseph(JV),Blaavand(MS),Kelstrup(GW),Rasmuss… Neuroscience 2026-04-16

...Sox2 and Olig2 but contains macrophages in the tumor stroma. The humane endpoint was reached after 6-8 weeks, allowing f...

Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemi…

Furukawa(T),Kumegawa(K),Miyata(K),Takamatsu(… J Exp Clin Cancer Res 2026-02-11

...SOX2 as potential upstream regulators of this gene program. CONCLUSIONS: This study established PDOX models that isolate...

Pachymic acid targets PDIA6 to delay mesenchymal stem cell senescence through t…

Yang(X),Xu(Y),Zhang(R),Xu(JY),Chen(WT),Chen(… J Adv Res 2026-02-16

...Sox2, restored the differentiation potential, and enhanced colony formation. Mechanistically, PA was bound specifically ...

Vesicular Glutamate Release Is Necessary for Neural Tube Formation.

Goyal(R),Castro(PA),Levin(JB),Shim(S),Balash… J Neurosci 2026-03-18

...Sox2, neural stem cell transcription factor, and neural plate cell proliferation. Exposure during early pregnancy to neu...

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