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Evolutionary evidence of tumor necrosis factor super family members in the Ja...

Biswas(Gouranga),Kinoshita(Shunsuke),Kono(... Mar Genomics 2016-03-24

...TNFSF12 (TWEAK), two TNFSF13B (BAFF) (1 and 2) and TNFSF14 (LIGHT) belonging to seven TNFSFs in Fugu. Several features s...

A combined omics approach to evaluate the effects of dietary curcumin on colo...

Cooney(Janine M),Barnett(Matthew P G),Domm... J Nutr Biochem 2016-10-20

...TNFSF12 and PI3K complex) activated in inflammation were down-regulated by dietary intervention with curcumin.

TWEAK/Fn14 interaction promotes oxidative stress through NADPH oxidase activa...

Madrigal-Matute(Julio),Fernandez-Laso(Valv... Cardiovasc Res 2016-09-02

The interaction between TNF-like weak inducer of apoptosis (TWEAK, Tnfsf12) and the receptor, fibroblast growth factor-i...

The TWEAK Receptor Fn14 Is an Src-Inducible Protein and a Positive Regulator ...

Cheng(Emily),Whitsett(Timothy G),Tran(Nhan... Mol Cancer Res 2016-02-01

...TNFSF12).,Fn14 engagement stimulates multiple signal transduction pathways, including the NF-κB pathway, and this trigge...

Genetic deletion or TWEAK blocking antibody administration reduce atheroscler...

Sastre(Cristina),Fernández-Laso(Valvanera)... J Cell Mol Med 2015-04-02

...TNFSF12 and Apolipoprotein E (TNFSF12(-/-) ApoE(-/-) ) exhibited a diminished atherosclerotic burden and lesion size in ...

TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in ...

Doerner(Jessica L),Wen(Jing),Xia(Yumin),Pa... J Invest Dermatol 2015-11-16

...TNFSF12) and its sole receptor Fn14, belonging to the TNF ligand and receptor superfamilies respectively, are involved i...

Knockdown of specific host factors protects against influenza virus-induced c...

Tran(A T),Rahim(M N),Ranadheera(C),Kroeker... Cell Death Dis 2014-03-12

...TNFSF12-TNFSF13 (TWE-PRIL) and USP47, were selected because of the high levels of protection conferred by their silencin...

TWEAK/Fn14 Axis-Targeted Therapeutics: Moving Basic Science Discoveries to th...

Cheng(Emily),Armstrong(Cheryl L),Galisteo(... Front Immunol 2014-05-13

...TNFSF12) is a multifunctional cytokine implicated in physiological tissue regeneration and wound repair. TWEAK is initia...

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinicall...

Szarc vel Szic(Katarzyna),Op de Beeck(Ken)... PLoS One 2014-10-20

...TNFSF12, IL6, ANGPTL2, CSF1R) and concomitant increased expression of the validated breast cancer metastasis suppressor ...

Minocycline modulates cytokine and gene expression profiles in the brain afte...

Mehrotra(Shalini),Pecaut(Michael J),Gridle... In Vivo 2014-09-04

...Tnfsf12, Il12b and Il1f8, these were no longer up-regulated in the minocycline-treated groups. Similarly, the pro-apopto...

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