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Meta-analysis and brain imaging data support the involvement of VRK2 (rs23121...

Li(Ming),Wang(Yi),Zheng(Xue-bin),Ikeda(Mas... Schizophr Res 2013-05-07

...VRK2 in schizophrenia patients. Our data provide further evidence for the contribution of VRK2 to schizophrenia.

Human VRK2 (vaccinia-related kinase 2) modulates tumor cell invasion by hyper...

Vázquez-Cedeira(Marta),Lazo(Pedro A) J Biol Chem 2013-02-14

...VRK2 directly interacts and phosphorylates NFAT1 in Ser-32 within its N-terminal transactivation domain. VRK2 increases ...

Role of bivalent cations in structural stabilities of new drug targets--vacci...

Fu(Ting),Ren(Hong),Zhang(Jiajing),Ren(Peng... Curr Pharm Des 2013-09-05

...VRK2, and Mn²⁺ was slightly required for VRK2. By contrast, the pseudokinase VRK3 was well ordered with lower RMSD value...

VRK2 identifies a subgroup of primary high-grade astrocytomas with a better p...

Rodríguez-Hernández(Irene),Vázquez-Cedeira... BMC Clin Pathol 2013-11-15

...VRK2 was studied by analyzing the growth characteristics of astrocytoma cell lines with different EGFR/VRK2 protein rati...

Rare Genomic Variants Link Bipolar Disorder with Anxiety Disorders to CREB-Re...

Kerner(Berit),Rao(Aliz R),Christensen(Bryc... Front Psychiatry 2013-12-18

...VRK2, MESDC2, and FGGY. The variants were shared among all three affected family members but absent in the unaffected si...

Human VRK2 modulates apoptosis by interaction with Bcl-xL and regulation of B...

Monsalve(D M),Merced(T),Fernández(I F),Bla... Cell Death Dis 2013-06-17

VRK2 is a novel Ser-Thr kinase whose VRK2A isoform is located in the endoplasmic reticulum and mitochondrial membranes. ...

Genetics of the epilepsies: where are we and where are we going?

Helbig(Ingo),Lowenstein(Daniel H) Curr Opin Neurol 2013-08-22

...VRK2, PNPO and SCN1A. Furthermore, a landmark study provided evidence that screening for the HLA-B1502 variant may preve...

Sensitivity of the kinase activity of human vaccinia-related kinase proteins ...

Barcia-Sanjurjo(Iria),Vázquez-Cedeira(Mart... J Biol Inorg Chem 2013-09-24

The human vaccinia-related kinase (VRK) proteins VRK1 and VRK2 regulate different processes, such as the cell cycle, DNA...

Substrate profiling of human vaccinia-related kinases identifies coilin, a Ca...

Sanz-García(Marta),Vázquez-Cedeira(Marta),... J Proteomics 2012-03-29

...VRK2) using a human peptide-array containing 1080 sequences phosphorylated in known signaling pathways has been studied....

Screening of candidate genes for primary open angle glaucoma.

Liu(Ting),Xie(Lin),Ye(Jian),Liu(Yuewuyang)... Mol Vis 2012-12-21

...VRK2), F-box protein 11 (FBXO11), EGF containing fibulin-like extracellular matrix protein 1 (EFEMP1), reticulon 4 (RTN4...

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