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Peripheral blood derived mononuclear cells enhance osteoarthritic human chond...

Hopper(Niina),Henson(Frances),Brooks(Roger... Arthritis Res Ther 2016-04-08

...COL2A1 600-fold, p < 0.0001) and SRY box 9 (SOX9 30-fold, p < 0.0001) and the mRNA levels of 7 genes central in cell mot...

The Wnt11 Signaling Pathway in Potential Cellular EMT and Osteochondral Diffe...

He(Deng),Lu(Yuchao),Hu(Henglong),Zhang(Jia... Int J Mol Sci 2016-04-18

...Col2A1, OPN, Sox9, Runx2) and decreased epithelial phenotypes (E-cadherin, CK19) bythe detection of mRNAs and correspond...

Improved properties of bone and cartilage tissue from 3D inkjet-bioprinted hu...

Gao(Guifang),Schilling(Arndt F),Hubbell(Ka... Biotechnol Lett 2016-06-23

...Col2A1, ACAN) was improved by PEG-GelMA in comparison to PEG alone. These observations were consistent with the histolog...

Reciprocal activation of hypoxia-inducible factor (HIF)-2α and the zinc-ZIP8-...

Lee(M),Won(Y),Shin(Y),Kim(J-H),Chun(J-S) Osteoarthritis Cartilage 2016-09-26

...Col2a1-Cre), ZIP8 (Zip8(fl/fl);Col2a1-Cre), or MTF1 (Mtf1(fl/fl);Col2a1-Cre).,HIF-2α activated the zinc-ZIP8-MTF1 axis i...

Comparison of human mesenchymal stem cells derived from bone marrow, synovial...

Isobe(Y),Koyama(N),Nakao(K),Osawa(K),Ikeno... Int J Oral Maxillofac Surg 2016-10-10

...COL2A1 and COL10A1 by real-time PCR. In terms of adipogenesis, lipid vesicles were observed in the BMMSCs and SFCs. Dent...

BAPX-1/NKX-3.2 acts as a chondrocyte hypertrophy molecular switch in osteoart...

Caron(Marjolein M J),Emans(Pieter J),Surte... Arthritis Rheumatol 2016-02-02

...COL2A1, or aggrecan, but led to an acute hypertrophic shift in the HAC phenotype. Overexpression of BAPX-1/NKX-3.2 decre...

CaMKII plays a part in the chondrogenesis of bone marrow-derived mesenchymal ...

Qu(Feng),Zhao(Zhikun),Yuan(Bangtuo),Qi(Wei... Int J Clin Exp Pathol 2016-04-21

...COL2A1, Aggrecan and SOX9 in BMSCs were gained by real-time fluorescence quantitative polymerase chain reaction (RT-QPCR...

Novel COL2A1 variant (c.619G&gt;A, p.Gly207Arg) manifesting as a phenotype simil...

Jurgens(Julie),Sobreira(Nara),Modaff(Peggy... Hum Mutat 2016-06-29

...COL2A1 variant and were matched following discussion at an academic conference. In the first family, we performed whole-...

Cartilage development requires the function of Estrogen-related receptor alph...

Kim(Yong-Il),No Lee(Joon),Bhandari(Sushil)... Sci Rep 2016-10-13

...col2a1, sox5, sox6, runx2 and col10a1 thus induces abnormally formed cartilage in pharyngeal arches. Importantly, we ide...

The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity...

Dudek(Michal),Gossan(Nicole),Yang(Nan),Im(... J Clin Invest 2016-06-17

...Col2a1, but increased p-SMAD1/5 levels. Together, these results define a regulatory mechanism that links chondrocyte BMA...

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