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CD95L cell surface cleavage triggers a prometastatic signaling pathway in tri...

Malleter(Marine),Tauzin(Sébastien),Bessede... Cancer Res 2014-01-23

...Orai1-EGFR-PI3K pathway that triggered migration of TNBC cells exposed to CD95L. Our findings establish a prometastatic ...

Inhibition of STIM1 phosphorylation underlies resveratrol-induced inhibition ...

Casas-Rua(Vanessa),Alvarez(Ignacio S),Pozo... Biochem Pharmacol 2014-01-07

...ORAI1. Although additional targets for resveratrol in the molecular mechanism that governs SOCE cannot be discarded, the...

The STIM1/Orai signaling machinery.

Fahrner(Marc),Derler(Isabella),Jardin(Isaa... Channels (Austin) 2014-09-04

...Orai1 coupling to the ultimate Orai1 channel activation and permeation.

Activation of the endoplasmic reticulum calcium sensor STIM1 and store-operat...

Hyser(Joseph M),Utama(Budi),Crawford(Sue E... J Virol 2014-02-05

...Orai1 SOCE calcium channel. Expression of wild-type NSP4 activated STIM1, resulting in PM calcium influx, but an NSP4 vi...

Amelioration of Muc5b mucin hypersecretion is enhanced by IL-33 after 2-APB a...

Lin(L),Zhao(X),Yan(W),Guo(Y),Liang(S) Biotech Histochem 2014-12-03

...Orai1, Muc5b, IL-4, IL-5, IL-13 and IL-33 in mouse nasal lavage fluid (NLF) and nasal mucosa were determined using enzym...

TGFβ1 and SGK1-sensitive store-operated Ca2+ entry and Orai1 expression in en...

Schmidt(S),Schneider(S),Yang(W),Liu(G),Sch... Mol Hum Reprod 2014-08-21

...Orai1 is expressed in endometrium and sensitive to regulation by SGK1 and/or TGFβ1. To this end, Orai1 protein abundance...

Modulation of T Cell Metabolism and Function through Calcium Signaling.

Fracchia(Kelley M),Pai(Christine Y),Walsh(... Front Immunol 2014-06-24

...Orai1/2 proteins in the regulation of store-operated/calcium release activated calcium (CRAC) channels in the context of...

Structural aspects of calcium-release activated calcium channel function.

Stathopulos(Peter B),Ikura(Mitsuhiko) Channels (Austin) 2014-09-04

...Orai1 N-terminal fragment in complex with calmodulin. The accessible structural data are discussed in terms of potential...

Quantifying SOCE fluorescence measurements in mammalian muscle fibres. The ef...

Bolaños(Pura),Guillen(Alis),Gámez(Adriana)... J Muscle Res Cell Motil 2014-09-17

...Orai1 and stromal interaction molecule and the sarcoplasmic reticulum and plasma membranes, in the triadic junctional re...

STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+...

Weidinger(Carl),Shaw(Patrick J),Feske(Stefan) EMBO Mol Med 2014-03-10

...ORAI1 or STIM1 are immunodeficient and are prone to develop virus-associated tumours. This and the reported role of Ca(2...

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