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Interferon-gamma up-regulates expression and activity of P-glycoprotein in huma…

Puddu(P),Fais(S),Luciani(F),Gherardi(G),Dupu… Lab Invest 1999-10-00

...Pgp in human peripheral blood monocyte-derived macrophages (MDM). We report that IFN-gamma up-regulated Pgp expression i...

The effect of prolil-glycil-proline (PGP) peptide and PGP-rich substances on ha…

Lyapina(LA),Pastorova(VE),Samonina(GE),Ashma… Blood Coagul Fibrinolysis 2000-07-00

...PGP administration. Therefore, PGP and some PGP-rich substances can be qualified as potent anticoagulant and antithrombo...

Differential effects of mitomycin C and doxorubicin on P-glycoprotein expressio…

Maitra(R),Halpin(PA),Karlson(KH),Page(RL),Pa… Biochem J 2001-05-01

...Pgp expression and function. Doxorubicin caused a progressive increase in the cell-surface expression of Pgp and functio...

Allosteric modulation of the human P-glycoprotein involves conformational chang…

Ghosh(Pratiti),Moitra(Karobi),Maki(Nazli),De… Arch Biochem Biophys 2006-07-11

...Pgp modulators with an allosteric mode of action induce a distinct conformational change in the cytosolic domain of Pgp,...

Cardiomyocytes of chronically ischemic pig hearts express the MDR-1 gene-encode…

Lazarowski(Alberto J),García Rivello(Hernán … J Histochem Cytochem 2005-07-29

...Pgp-170) is not normally present in the cardiomyocyte. Given that in other tissues Pgp-170 is not found under normoxic c...

P-glycoprotein (PGP) and lung resistance-related protein (LRP) expression and f…

Michieli(M),Damiani(D),Ermacora(A),Raspadori… Br J Haematol 1997-02-00

...PGP, 11% only LRP, 1.5% only MRP, 24.5% both PGP and LRP, and 4.5% both PGP and MRP. The mean intracellular daunorubicin...

Protein gene product (PGP) 9.5 immunoreactivity in nerve fibres and pinealocyte…

Romeo(HE),Weihe(E),Müller(S),Vollrath(L) Cell Tissue Res 1993-03-00

...PGP) 9.5 in pinealocytes and nerve fibres of guinea-pig pineal gland. The pattern of PGP 9.5-immunoreactive (ir) nerve f...

Activation of CXCR2 by extracellular matrix degradation product acetylated Pro-…

Kim(Sang Doo),Lee(Ha Young),Shim(Jae Woong),… Am J Respir Crit Care Med 2011-09-27

...PGP bound directly to CXCR2, and the protective effect of Ac-PGP in sepsis was abolished in CXCR2-deficient mice. Ac-PGP...

Effects of grapefruit juice on the multidrug transporter P-glycoprotein in the …

Romiti(Nadia),Tramonti(Gianfranco),Donati(An… Life Sci 2004-12-08

...Pgp dependent transport by GFJ may lead to changes in bioavailability of drugs that are substrates of Pgp itself, by aff...

In vivo and in vitro multitracer analyses of P-glycoprotein expression-related …

Márián(T),Szabó(G),Goda(K),Nagy(H),Szincsák(… Eur J Nucl Med Mol Imaging 2003-08-00

...Pgp(+)/Pgp(-) =0.61+/-0.13; P<0.01) and cells in vitro (Pgp(+)/Pgp(-) =0.08+/-0.01; P<0.001).()Cyclosporin A reversed (9...

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