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The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism f…

Jauch(Ralf),Ng(Calista K L),Narasimhan(Kames… Biochem J 2012-05-21

...Sox17 and Sox2, we observed subtle conformational differences at the DNA-binding interface. Furthermore, using quantitat...

Hypermethylation of Sox17 gene is useful as a molecular diagnostic application …

Oishi(Yoshichika),Watanabe(Yoshiyuki),Yoshid… Tumour Biol 2012-04-30

...Sox17. Sox17 showed significant differential methylation between pre- and post-treatments in EGC patients (Sox17, p < 0....

Genome-wide CpG island profiling of intraductal papillary mucinous neoplasms of…

Hong(Seung-Mo),Omura(Noriyuki),Vincent(Audre… Clin Cancer Res 2012-05-24

...SOX17, NXPH1, EBF3) were significantly more likely to be methylated in IPMNs with high-grade than with low-grade dysplas...

Primitive endoderm differentiates via a three-step mechanism involving Nanog an…

Frankenberg(Stephen),Gerbe(François),Bessonn… Dev Cell 2012-02-13

...Sox17 and Gata4--later markers of the PrE--depends on the presence of Fgf4 produced by Nanog-expressing cells. Thus, our...

Involvement of histone acetylation of Sox17 and Foxa2 promoters during mouse de…

Fu(Shijun),Fei(Qi),Jiang(Hua),Chuai(Shannon)… PLoS One 2012-04-02

...Sox17 and Foxa2 are subjected to histone acetylation regulation. Administration of Hdac inhibitors greatly augmented DE ...

[Transcriptomic regulation and molecular mechanism of polygenic tumor at differ…

Li(Xiayu),Shen(Shourong),Wu(Minghua),Li(Xiao… Zhong Nan Da Xue Xue Bao Yi X… 2012-09-06

...SOX17, NGX6, SOX7, and LRRC4 have been identified as the key transcriptional regulation genes during the stage of tumor ...

Stimulation of Activin A/Nodal signaling is insufficient to induce definitive e…

Filby(Caitlin E),Williamson(Robert),van Kooy… Stem Cell Res Ther 2012-09-27

...Sox17, FOXA2 and TTF1) and lung epithelium (surfactant protein C; SPC) and cystic fibrosis transmembrane conductance reg...

Prospective isolation and characterization of bipotent progenitor cells in earl…

Okada(Ken),Kamiya(Akihide),Ito(Keiichi),Yana… Stem Cells Dev 2012-08-10

...Sox17, endodermal progenitor cell markers, was highest at E9.5 but decreased dramatically thereafter. These first prospe...

A model of early human embryonic stem cell differentiation reveals inter- and i…

Galat(Vasiliy),Malchenko(Sergey),Galat(Yekat… Stem Cells Dev 2012-08-29

...Sox17) point to a mesendodermal nature of the epithelial cells with subsequent commitment to definitive endoderm (Sox17,...

Activin, BMP and FGF pathways cooperate to promote endoderm and pancreatic line…

Xu(Xiaofang),Browning(Victoria L),Odorico(Jo… Mech Dev 2012-03-19

...SOX17 and FOXA2. Early proliferative foregut endoderm and pancreatic lineage cells marked by PDX1, FOXA2 and SOX9 expres...

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