...Orai1, and TRPC1. Co-immunoprecipitation experiments showed that UII promoted the association between Orai1 and STIM1, a...
...Orai1/STIM1, ROMK, KCNE1/KCNQ1, GluR6, CFTR). SGK1 further up-regulates a number of enzymes (e.g. glycogen-synthase-kina...
...Orai1 as a prototypic CRAC channel protein and STIM1 as the endoplasmic reticulum (ER) Ca(2+) sensor has led to rapid pr...
...ORAI1 are the fundamental working machinery of the CRAC channel, a classical pathway for store-operated Ca(2+) entry. Th...
STIM1 and Orai1 are two essential components of the calcium release-activated calcium (CRAC) channel. Recently, distinct...
...Orai1. STIM1 activates Orai channels by a mechanism that depends upon its colocalization with Orai at endoplasmic reticu...
...Orai1 subunits, the ARC channel is formed by a combination of Orai1 and Orai3 subunits. Moreover, while STIM1 in the mem...
...Orai1, which determines the activation of TRPC1. Orai1-mediated Ca(2+) entry is required for recruitment of TRPC1 and it...
...Orai1 as the pore subunit of CRAC channels has provided the much-needed molecular tool to dissect the mechanism of activ...
...Orai1 in their store-dependent mode, emerging evidence suggests that Orai1 and Orai3 heteromultimeric channels can form ...
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