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Urotensin-II promotes vascular smooth muscle cell proliferation through store...

Rodríguez-Moyano(María),Díaz(Ignacio),Dion... Cardiovasc Res 2014-07-01

...Orai1, and TRPC1. Co-immunoprecipitation experiments showed that UII promoted the association between Orai1 and STIM1, a...

Serum and glucocorticoid inducible kinase, metabolic syndrome, inflammation, ...

Lang(Florian),Stournaras(Christos) Hormones (Athens) 2014-03-10

...Orai1/STIM1, ROMK, KCNE1/KCNQ1, GluR6, CFTR). SGK1 further up-regulates a number of enzymes (e.g. glycogen-synthase-kina...

Store-operated Orai channels: structure and function.

Prakriya(Murali) Curr Top Membr 2014-02-11

...Orai1 as a prototypic CRAC channel protein and STIM1 as the endoplasmic reticulum (ER) Ca(2+) sensor has led to rapid pr...

STIM-ORAI interactions that control the CRAC channel.

Gudlur(Aparna),Zhou(Yubin),Hogan(Patrick G... Curr Top Membr 2014-02-11

...ORAI1 are the fundamental working machinery of the CRAC channel, a classical pathway for store-operated Ca(2+) entry. Th...

On the stoichiometry of resting and activated CRAC channels.

Chen(Liangyi),Xu(Tao) Curr Top Membr 2014-02-11

STIM1 and Orai1 are two essential components of the calcium release-activated calcium (CRAC) channel. Recently, distinct...

Alternative forms of the store-operated calcium entry mediators, STIM1 and Or...

Putney(James W) Curr Top Membr 2014-02-11

...Orai1. STIM1 activates Orai channels by a mechanism that depends upon its colocalization with Orai at endoplasmic reticu...

The ARC channel--an endogenous store-independent Orai channel.

Thompson(Jill L),Mignen(Olivier),Shuttlewo... Curr Top Membr 2014-02-11

...Orai1 subunits, the ARC channel is formed by a combination of Orai1 and Orai3 subunits. Moreover, while STIM1 in the mem...

Contribution and regulation of TRPC channels in store-operated Ca2+ entry.

Cheng(Kwong Tai),Ong(Hwei Ling),Liu(Xibao)... Curr Top Membr 2014-02-11

...Orai1, which determines the activation of TRPC1. Orai1-mediated Ca(2+) entry is required for recruitment of TRPC1 and it...

Molecular regulation of the pore component of CRAC channels, Orai1.

Srikanth(Sonal),Gwack(Yousang) Curr Top Membr 2014-02-11

...Orai1 as the pore subunit of CRAC channels has provided the much-needed molecular tool to dissect the mechanism of activ...

Emerging roles for native Orai Ca2+ channels in cardiovascular disease.

Ruhle(Brian),Trebak(Mohamed) Curr Top Membr 2014-02-11

...Orai1 in their store-dependent mode, emerging evidence suggests that Orai1 and Orai3 heteromultimeric channels can form ...

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