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Oncogenic HoxB7 requires TALE cofactors and is inactivated by a dominant-negati…

Fernandez(Luis C),Errico(M C),Bottero(L),Pen… Cancer Lett 2008-08-27

...Pbx1 mutant, Pbx1NT, which sequesters Prep1 in the cytoplasm. The less aggressive phenotype of the SkBr3/B7/PbxNT cells,...

Detection of a t(1;22)(q23;q12) translocation leading to an EWSR1-PBX1 fusion g…

Brandal(Petter),Panagopoulos(Ioannis),Bjerke… Genes Chromosomes Cancer 2008-06-26

...PBX1 fusion gene consisting of exons 1-8 of the 5'-end of EWSR1 and exons 5-9 of the 3'-end of PBX1 was shown to result ...

Evaluating the association of common PBX1 variants with type 2 diabetes.

Duesing(Konsta),Charpentier(Guillaume),Marre… BMC Med Genet 2008-04-16

...PBX1 locus in 3,093 subjects to test for association with type 2 diabetes.,Several PBX1 SNPs, including the G21S coding ...

Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia.

Bijl(J),Krosl(J),Lebert-Ghali(C-E),Vacher(J)… Oncogene 2008-11-24

...PBX1 in lymphoid tumors. To further explore this possibility, we generated a series of compound E2A-PBX1 x Hox transgeni...

BCR-ABL, ETV6-RUNX1 and E2A-PBX1: prevalence of the most common acute lymphobla…

Jiménez-Morales(S),Miranda-Peralta(E),Saldañ… Leuk Res 2008-08-28

...PBX1. The prevalence of E2A-PBX1 is one of the highest that has been described thus far in childhood ALL. Furthermore, w...

Tumor classification ranking from microarray data.

Hewett(Rattikorn),Kijsanayothin(Phongphun) BMC Genomics 2008-11-05

...PBX1, MALL and TALL. SVM (Support Vector Machine) gives the highest AUC for the classifications of lung, lymphoma, and b...

Pbx1 functions in distinct regulatory networks to pattern the great arteries an…

Chang(Ching-Pin),Stankunas(Kryn),Shang(Ching… Development 2008-12-31

...Pbx1-null embryos remain within the same spectrum as those of Pbx1-null embryos. Thus, Pbx1 makes a crucial contribution...

Cytosolic sequestration of Prep1 influences early stages of T cell development.

Penkov(Dmitry),Palazzolo(Martina),Mondino(An… PLoS One 2008-08-20

...Pbx1 (Pbx1NT) under the control of the Lck proximal promoter.,Pbx1NT causes Prep1 cytosolic sequestration, abolishes Pre...

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart dise…

Stankunas(Kryn),Shang(Ching),Twu(Karen Y),Ka… Circ Res 2008-10-27

...Pbx1, whose inactivation results in persistent truncus arteriosus. Reduction or absence of Pbx2 or Pbx3 leads to Pbx1 ha...

p160 Myb-binding protein interacts with Prep1 and inhibits its transcriptional …

Díaz(Víctor M),Mori(Silvia),Longobardi(Elena… Mol Cell Biol 2008-03-26

Prep1 is known to interact in vivo with Pbx1 to regulate development and organogenesis. We have identified a novel Prep1...

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