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Generating human intestinal tissue from pluripotent stem cells in vitro.

McCracken(Kyle W),Howell(Jonathan C),Wells(J… Nat Protoc 2012-08-16

...SOX17(+) endoderm by treating the cells with activin A for 3 d. After endoderm induction, the pluripotent stem cells are...

Multifactorial origins of heart and gut defects in nipbl-deficient zebrafish, a…

Muto(Akihiko),Calof(Anne L),Lander(Arthur D)… PLoS Biol 2012-02-24

...sox17, foxa2, and gata5) and left-right patterning (spaw, lefty2, and dnah9) is altered. Experimental manipulation of th...

The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism f…

Jauch(Ralf),Ng(Calista K L),Narasimhan(Kames… Biochem J 2012-05-21

...Sox17 and Sox2, we observed subtle conformational differences at the DNA-binding interface. Furthermore, using quantitat...

Induction and selection of Sox17-expressing endoderm cells generated from murin…

Schroeder(Insa S),Sulzbacher(Sabine),Nolden(… Cells Tissues Organs 2012-11-28

...Sox17 locus into the endoderm lineage. Sox17-expressing cells were selected by fluorescence-assisted cell sorting (FACS)...

Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bi…

Carpino(Guido),Cardinale(Vincenzo),Onori(Pao… J Anat 2012-03-06

...SOX17, EpCAM, NCAM, CXCR4, Lgr5, OCT4) but not for mature markers (e.g. albumin, secretin receptor or insulin). Subpopul...

The differentiation and isolation of mouse embryonic stem cells toward hepatocy…

Meng(Qingyuan),Haque(Amranul),Hexig(Bayar),A… Biomaterials 2012-04-02

...Sox17(+)) and the ones toward another cell lineage (brachyury(+) and Pdx1(+)). The system uses a glycopolymer as an extr...

The Sox17-mCherry fusion mouse line allows visualization of endoderm and vascul…

Burtscher(Ingo),Barkey(Wenke),Schwarzfischer… Genesis 2012-11-05

Sox17 is a HMG-box transcription factor that has been shown to play important roles in both cardio-vascular development ...

New prognostic markers and potential therapeutic targets in human testicular ge…

Chieffi(P) Curr Med Chem 2012-04-25

...SOX17, HMGA1, HMGA2, PATZ1, GPR30, Aurora B, and others has given further advantages to discriminate between histologica...

Differentiation of human labia minora dermis-derived fibroblasts into insulin-p…

Kim(Bona),Yoon(Byung Sun),Moon(Jai Hee),Kim(… Exp Mol Med 2012-06-06

...Sox17, Foxa2, and PDX1 (stage 2: mesenchymal-endoderm transition). In stage 3, cells in the mesenchymal- endoderm transi...

A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 …

Whipple(C A),Young(A L),Korc(M) Oncogene 2012-08-31

...SOX17), chemokine C-X3-C motif ligand 1 (CX3CL1) and integrin β3 (ITGB3). Moreover, pancreatic cancer cells isolated fro...

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