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An integrated analysis of mRNAs and lncRNAs in goat's hypothalamus to explore t…

Gao(X),Ren(C),Zhang(W),Fang(F) Reprod Domest Anim 2023-08-00

...TEAD4) associated with reproduction and puberty. Then, genetic correlation analysis of DE mRNAs and DE lncRNAs identifie...

Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-…

Troilo(A),Benson(EK),Esposito(D),Garibsingh(… Oncotarget 2016-05-17

...TEAD4, which did not inhibit the growth of Hippo wild-type cells with low levels of regulatable TEAD-mediated transcript...

Platr4 is an early embryonic lncRNA that exerts its function downstream on card…

Hazra(R),Brine(L),Garcia(L),Benz(B),Chirathi… Dev Cell 2022-00-07

...Tead4 to regulate the expression of a downstream target gene, Ctgf, which is crucial to the cardiac-lineage program. Imp...

In silico analysis of UCP promoters predicts conserved and human specific regul…

Tóth(BB),Hegedűs(G),Virág(E),Pethő(GT),Laczk… iScience 2025-07-18

...TEAD4) were UCP1-specific, others (e.g., PPARG and RXR) were shared by all UCPs. These results reveal conserved and spec...

Cell contact and Nf2/Merlin-dependent regulation of TEAD palmitoylation and act…

Kim(NG),Gumbiner(BM) Proc Natl Acad Sci U S A 2019-00-14

...TEAD4 mutant is unstable and degraded by proteasome through the activity of the E3 ubiquitin ligase CHIP. These findings...

Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer.

Corona(RI),Seo(JH),Lin(X),Hazelett(DJ),Reddy… Nat Commun 2020-00-24

...TEAD4 (P = 6 × 10-11) and its binding partner PAX8 (P = 2×10-10), a known lineage-specific transcription factor in OC. I...

N4-acetylcytidine of Nop2 mRNA is required for the transition of morula-to-blas…

Wang(M),Cheng(R),He(H),Han(Z),Zhang(Y),Wu(Q) Cell Mol Life Sci 2023-09-28

...TEAD4, resulting in defective expression of the downstream lineage-specific gene Cdx2, and ultimately preventing blastom...

ETV4 potentiates nuclear YAP retention and activities to enhance the progressio…

Xu(X),Wang(B),Liu(Y),Jing(T),Xu(G),Zhang(L),… Cancer Lett 2022-00-01

...TEAD4-mediated transcriptional activation in tumor cells. Functionally, the interplay of ETV4 and YAP promotes growth of...

N6-methyladenosine-modified VGLL1 promotes ovarian cancer metastasis through hi…

Li(H),Cai(L),Pan(Q),Jiang(X),Zhao(J),Xiang(T… iScience 2024-03-15

...TEAD4 and co-transcriptionally activates HMGA1. HMGA1 further activates Wnt/β-catenin signaling to enhance OC metastasis...

Chloroacetamide fragment library screening identifies new scaffolds for covalen…

Bum-Erdene(K),Ghozayel(MK),Zhang(MJ),Gonzale… RSC Med Chem 2023-09-19

...TEAD4 binding to YAP1. Here, we screen a fragment library of chloroacetamide electrophiles to identify new scaffolds tha...

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