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The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision.

Yu(R T),Chiang(M Y),Tanabe(T),Kobayashi(M),Y… Proc Natl Acad Sci U S A 2000-04-25

...Pax2 as a candidate target gene. This identification is significant, because Pax2 is known to be involved in retinal dev...

PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associa…

Lechner(M S),Levitan(I),Dressler(G R) Nucleic Acids Res 2000-09-07

...Pax2 and other Pax proteins. PTIP binds to Pax2 in vitro, in the yeast two-hybrid assay and in tissue culture cells. The...

Pax2 regulates neuronal-glial cell fate choice in the embryonic optic nerve.

Soukkarieh(Chadi),Agius(Eric),Soula(Cathy),C… Dev Biol 2007-04-26

...Pax2 which is maintained in differentiated astrocytes. We have observed that Pax2 is rapidly down-regulated in explanted...

[PAX gene function during kidney tumorigenesis: a comparative approach].

Béland(Mélanie),Bouchard(Maxime) Bull Cancer 2006-09-27

...PAX2/8 expression are frequently observed in cases of Wilm's tumor and renal cell carcinoma. The precise role of PAX2/8 ...

Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple s…

Batista(Manuel F),Lewis(Katharine E) Dev Biol 2008-11-24

...Pax2/8 transcription factors is very specific: in embryos in which Pax2a, Pax2b and Pax8 are simultaneously knocked-down...

Mutations of the PAX6 gene detected in patients with a variety of optic-nerve m…

Azuma(Noriyuki),Yamaguchi(Yuki),Handa(Hirosh… Am J Hum Genet 2003-07-22

...PAX2 promoter in a reporter assay. Because PAX2 gene mutations were detected in papillorenal syndrome, alternation of PA...

Determination of cell fates in the R7 equivalence group of the Drosophila eye b…

Shi(Yandong),Noll(Markus) Dev Biol 2009-07-08

...Pax2 play decisive roles in cone cell development and act in concert to transform developing R1/R6/R7 into cone cells: w...

Identification of Pax protein inhibitors that suppress target gene expression a…

Bradford(STJ),Grimley(E),Laszczyk(AM),Lee(PH… Cell Chem Biol 2022-00-17

...Pax2-positive cancer cell growth and target gene expression but has little effect on Pax2-negative cells. Chromatin immu...

Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.

Bouchard(Maxime),de Caprona(Dominique),Bussl… BMC Dev Biol 2010-11-16

...Pax2 expression can compensate for Pax8. Conversely, Pax8 cannot compensate for Pax2 leading to a cochlear phenotype not...

Ocular phenotype in a patient with PAX2 gene mutation-associated papillorenal s…

Benador-Shen(CL),Reichel(E),Reed(D),Milner(L… Ophthalmic Genet 2022-00-00

...PAX2 gene. A case report of papillorenal syndrome due to PAX2 mutation. Complete ophthalmologic examination was performe...

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