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Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration …

Tome-Garcia(J),Erfani(P),Nudelman(G),Tsankov… Nat Commun 2018-00-01

...TEAD4 in patient-derived GBM lines using CRISPR-Cas9. TEAD1 ablation robustly diminishes migration, both in vitro and in...

H3K79 methylation and H3K36 trimethylation synergistically regulate gene expres…

Cooke(EW),Zeng(C),Nur(SM),Jia(Y),Huang(A),Ch… Sci Adv 2025-07-04

...TEAD4 (TEA domain transcription factor 4) and its coactivator YAP1 (Yes-associated protein 1) to these enhancers. Furthe...

TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expressio…

Hwang(JH),Kim(AR),Kim(KM),Il Park(J),Oh(HT),… Nat Commun 2019-00-24

...Tead4 to induce Irs1 transcription. Finally, statin administration decreases TAZ, IRS1 level and insulin sensitivity. Ho...

YAP1 and QSER1 are Key Modulators of Embryonic Signaling Pathways in the Mammal…

Abraham(E),Roule(T),Douglas(A),Megill(E),Per… bioRxiv 2025-06-17

...TEAD4 enhancers recruit QSER1 to prevent RNA Polymerase II recruitment. Accordingly, QSER1 depletion, similar to YAP1, i...

Super-enhancer-guided mapping of regulatory networks controlling mouse trophobl…

Lee(BK),Jang(YJ),Kim(M),LeBlanc(L),Rhee(C),L… Nat Commun 2019-00-18

...Tead4), and >150 TFs that had not been previously implicated in TE lineage, that are SE-associated. Mapping targets of 2...

The Tumor Suppressor Interferon Regulatory Factor 2 Binding Protein 2 Regulates…

Feng(X),Lu(T),Li(J),Yang(R),Hu(L),Ye(Y),Mao(… Hepatology 2020-00-00

...TEAD4) transcriptional complex, inhibited YAP activity through a feedback loop. IRF2BP2 stabilized vestigial-like family...

ETV4 potentiates nuclear YAP retention and activities to enhance the progressio…

Xu(X),Wang(B),Liu(Y),Jing(T),Xu(G),Zhang(L),… Cancer Lett 2022-00-01

...TEAD4-mediated transcriptional activation in tumor cells. Functionally, the interplay of ETV4 and YAP promotes growth of...

YAP1 and QSER1 are key modulators of embryonic signaling pathways in the mammal…

Abraham(E),Roule(T),Douglas(A),Megill(E),Per… EMBO Rep 2026-05-00

...TEAD4 enhancers recruit QSER1 to prevent RNA Polymerase II recruitment. QSER1 depletion, similar to YAP1, increases NODA...

Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting Y…

Yu(M),Peng(Z),Qin(M),Liu(Y),Wang(J),Zhang(C)… Mol Cell 2021-00-18

...TEAD4, the histone acetyltransferase EP300, and Mediator1 and forms transcriptional hubs for maximizing target gene tran...

Lysophosphatidic Acid Accelerates Bovine In Vitro-Produced Blastocyst Formation…

Yu(B),van Tol(HTA),Oei(CHY),Stout(TAE),Roele… Int J Mol Sci 2021-05-31

...TEAD4 was up-regulated, and YAP was overexpressed, in LPA-treated day 6 embryos. However, LPA-induced up-regulation of C...

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