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The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of...

Caron(Marjolein M J),Emans(Pieter J),Sanen... PLoS One 2016-08-22

...Col2a1 and Col10a1 expression. Inhibition of COX-2 resulted in decreased Col10a1 expression, while Col2a1 remained unaff...

R-spondin 2 facilitates differentiation of proliferating chondrocytes into hy...

Takegami(Yasuhiko),Ohkawara(Bisei),Ito(Mik... Biochem Biophys Res Commun 2016-09-21

...Col2a1, Sox9, and Acan, as well as production of proteoglycans. In contrast, lentivirus-mediated knockdown of Rspo2 has ...

Minimal invasive annulotomy for induction of disc degeneration and implantati...

Xin(Long),Zhang(Chun),Zhong(Fuhua),Fan(Shu... Eur J Med Res 2016-10-17

...Col2A1 and matrix metalloprotease (MMP)-3 mRNA expression confirmed the disc degeneration, supporting the imaging result...

Assessment of the developmental toxicity of nanoparticles in an ex vivo 3D mo...

Bigaeva(Emilia),Paradis(France-Hélène),Moq... Nanotoxicology 2016-04-26

...Col2a1; Col10a1; Col1a1 triple transgenic fluorescent reporter mice, as revealed by changes in several morphological and...

Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Prolif...

Lamplot(Joseph D),Liu(Bo),Yin(Liangjun),Zh... Cell Transplant 2016-03-07

...Col2a1 and aggrecan and produce chondroid matrix in micromass culture. iMACs form subcutaneous cartilaginous masses in a...

Simulated microgravity affects chondrogenesis and hypertrophy of human mesenc...

Mayer-Wagner(Susanne),Hammerschmid(Florian... Int Orthop 2016-02-11

...COL2A1) were both significantly reduced. There was a higher decrease in COL2A1 than in COL10A1 expression, resulting in ...

Alternative protocols to induce chondrogenic differentiation: transforming gr...

Cicione(Claudia),Muiños-López(Emma),Hermid... Cell Tissue Bank 2016-02-16

...COL2A1, compared to the control points (p < 0.05, two-tailed t test). In our experimental conditions, the combination of...

A novel type II collagen gene mutation in a family with spondyloepiphyseal dy...

Nakashima(Yasuharu),Sakamoto(Yuma),Nishimu... Hum Genome Var 2016-06-09

...COL2A1) mutation and the family's phenotypic diversity. Clinical and radiographic examinations of skeletal dysplasia wer...

Novel mutations in the COL2A1 gene in Japanese patients with Stickler syndrom...

Kondo(Hiroyuki),Matsushita(Itsuka),Nagata(... Hum Genome Var 2016-07-13

...COL2A1 gene were identified, accounting for 21 of the 23 families. Different mutations of the COL2A1 gene were associate...

[Comparative proteomics study of different processing technology for pilose a...

Jin(Meng-ya),Dong(Ling),Luo(Yuan-ming),Yu(... Yao Xue Xue Bao 2016-05-26

...COL2A1). The significant function involves in platelets activating, maintenance of spermatogonium, and disorder expressi...

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