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KCa and Ca(2+) channels: the complex thought.

Guéguinou(Maxime),Chantôme(Aurélie),Fromon... Biochim Biophys Acta 2014-09-25

...Orai1 to Orai3) families and their partners STIM (STIM1 to STIM2). A depolarization is needed to activate voltage-gated ...

[Role of store-operated Ca2+ channels in ethanol-induced intracellular Ca2+ i...

Liu(Hui-min),Yan(Li-hui),Luo(Zheng),Sun(Xi... Zhonghua Gan Zang Bing Za Z... 2014-12-08

...Orai1) were evaluated by qPCR and western blotting.,The ethanol treatment produced dose-dependent reduction in cell viab...

The ryanodine receptor agonist 4-chloro-3-ethylphenol blocks ORAI store-opera...

Zeng(Bo),Chen(Gui-Lan),Daskoulidou(Nikolet... Br J Pharmacol 2014-10-28

...ORAI1-3, 4-CEP inhibited the ORAI1, ORAI2 and ORAI3 currents evoked by thapsigargin. The 2-APB-induced ORAI3 current was...

High glucose and diabetes enhanced store-operated Ca(2+) entry and increased ...

Chaudhari(Sarika),Wu(Peiwen),Wang(Yanxia),... Am J Physiol Renal Physiol 2014-06-19

...Orai1 protein expressions. HG upregulates STIM1 by promoting its transcription but increases Orai1 protein through a pos...

A dominant STIM1 mutation causes Stormorken syndrome.

Misceo(Doriana),Holmgren(Asbjørn),Louch(Wi... Hum Mutat 2014-12-12

...ORAI1, a Ca(2+) release-activated Ca(2+) channel located in the plasma membrane. The STIM1 mutation found in Stormorken ...

Activating mutations in STIM1 and ORAI1 cause overlapping syndromes of tubula...

Nesin(Vasyl),Wiley(Graham),Kousi(Maria),On... Proc Natl Acad Sci U S A 2014-05-29

...ORAI1 or the Ca(2+) sensing protein stromal interaction molecule 1 (STIM1) result in severe immune dysfunction and nonpr...

Store-operated Ca²⁺ entry mediated regulation of polarization in differentiat...

Ma(Shuang),Cai(Chunqing),Ma(Yan),Bai(Zheng... Mol Med Rep 2014-09-24

...Orai1 expression in dHL-60 cells during hypoxia, and it was observed that the expression of STIM1 and Orai1 was signific...

Suppression of STIM1 in the early stage after global ischemia attenuates the ...

Zhang(Ming),Song(Jin-Ning),Wu(Yuan),Zhao(Y... Neuroreport 2014-11-28

...ORAI1 expression in the hippocampus increased continuously after global ischemia and peaked on day 4. These data were co...

Decreased store operated Ca2+ entry in dendritic cells isolated from mice exp...

Schmid(Evi),Yan(Jing),Nurbaeva(Meerim K),R... PLoS One 2014-10-28

...Orai1, K(+)-dependent Na(+)/Ca(2+)-exchangers (NCKX), K(+)-independent Na(+)/Ca(2+)-exchangers (NCX) and calbindin-D28k....

1,25(OH)2 vitamin D3-dependent inhibition of platelet Ca2+ signaling and thro...

Borst(Oliver),Münzer(Patrick),Schmid(Evi),... FASEB J 2014-06-16

...Orai1 and its regulator STIM1. In other cells, Ca(2+) transport is regulated by 1,25(OH)2 vitamin D3 [1,25(OH)2D3]. 1,25...

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