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Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype …

Sango(K),Yamanaka(S),Hoffmann(A),Okuda(Y),Gr… Nat Genet 1995-11-02

...Hexa and Hexb genes in embryonic stem cells, we have established mouse models corresponding to each disease. Unlike the ...

Purification and characterization of recombinant squalene epoxidase.

Nagumo(A),Kamei(T),Sakakibara(J),Ono(T) J Lipid Res 1995-12-07

...hexa-histidine in the C-terminal were added. Purification was carried out using Ni-chelate affinity agarose and Cibacron...

Circulation of oligonucleotides by disulfide bridge formation.

Gao(H),Yang(M),Patel(R),Cook(A F) Nucleic Acids Res 1995-08-03

...hexamethylenethiol groups, followed by oxidation of the thiol groups with air of oxygen to produce the corresponding cir...

Sulfated oligosaccharides promote hepatocyte growth factor association and gove…

Zioncheck(T F),Richardson(L),Liu(J),Chang(L)… J Biol Chem 1995-08-25

...hexa-, hepta-, or a sulfated oligosaccharide mixture containing decasaccharides resulted in an approximate 2-, 4-, and 7...

Effects of some novel D-myo-inositol-phosphate derivatives on binding and sympa…

Sun(X Y),Edvinsson(L),Yoo(H),Wahlestedt(C),H… J Cardiovasc Pharmacol 1995-09-05

...hexa-phosphate (InsP6, phytic acid) were studied in binding assays in rat heart membranes, in vitro in isolated guinea p...

[Inborn errors of metabolism due to mutations in isoenzyme genes].

Takagi(Y) Nihon Rinsho 1995-08-07

...HEXA and HEXB, respectively) deficiencies. Gene analysis revealed a 5'-defect and point mutation in patients with Tay-Sa...

Neuropathology of mice with targeted disruption of Hexa gene, a model of Tay-Sa…

Taniike(M),Yamanaka(S),Proia(R L),Langaman(C… Acta Neuropathol 1995-08-17

...Hexa gene encoding the subunit of alpha-hexosaminidase A. The mice were completely devoid of beta-hexosaminidase A activ...

The uniform galactose 4-sulfate structure in the carbohydrate-protein linkage r…

Yamada(S),Oyama(M),Yuki(Y),Kato(K),Sugahara(… Eur J Biochem 1995-12-18

...hexasaccharide alditol had the following structure: delta HexA alpha 1-3GalNAc(4-sulfate) beta 1-4GlcA beta 1- 3Gal(4-su...

Lipopolysaccharide of Rhodospirillum salinarum 40: structural studies on the co…

Rau(H),Seydel(U),Freudenberg(M),Weckesser(J)… Arch Microbiol 1995-12-22

...HexA (1 --> 4)HexA(1 --> 5)Kdo-trisaccharide was identified by methylation analysis. The terminal HexA (hexuronic acid) ...

Renal function and serum fluoride concentrations in patients with stable renal …

Conzen(P F),Nuscheler(M),Melotte(A),Verhaege… Anesth Analg 1995-09-26

...hexa-fluoro-isopropanol and inorganic fluoride by the human liver. Its use as an anesthetic may lead to peak plasma fluo...

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