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Identification of resistance mechanisms to small-molecule inhibition of TEAD-re…

Kulkarni(A),Mohan(V),Tang(TT),Post(L),Chan(Y… EMBO Rep 2024-09-00

...TEAD4 DNA-binding proteins. Recently, several small-molecule inhibitors of YAP and TEADs have been reported, with some e...

YAP-LAMB3 axis dictates cellular resistance of pancreatic ductal adenocarcinoma…

Li(Y),Wang(X),Yu(H),Cao(J),Xie(J),Zhou(J),Fe… Mol Carcinog 2024-10-00

...TEAD4 to amplify YAP signaling via a feedback loop. Such a YAP-LAMB3 axis is critical to induce epithelial-mesenchymal t...

Pan-cancer analysis of the prognostic and immunological role of hippo-YAP signa…

Yang(J),Yang(C),Yang(G),Wang(R),Li(J),Song(Y) Discov Oncol 2024-09-27

...TEAD4, MAP4K4, and STK3) might affect the prognosis of patients with skin cutaneous melanoma (SKCM) and pancreatic adeno...

SRC activates TAZ for intestinal tumorigenesis and regeneration.

Byun(MR),Hwang(JH),Kim(AR),Kim(KM),Park(JI),… Cancer Lett 2017-00-01

...TEAD4)-mediated transcription. However, a TAZ phosphorylation mutant significantly decreased cell proliferation, wound h...

Histone chaperone APLF level dictates the implantation of mouse embryos.

Varghese(PC),Rajam(SM),Nandy(D),Jory(A),Mukh… J Cell Sci 2021-00-13

...Tead4, and the gain in Cdh1 and sFlt1 (also known as Flt1) level, marked the differentiation of APLF-knocked down tropho...

Arginine methyltransferase PRMT1 equipoises trophoblast development to prevent …

Dasgupta(P),Kumar(R),Ray(S),Roy(N),Niloy(AJ)… Nat Commun 2026-07-10

...TEAD4 and MYBL2, through enrichment of histone H4 arginine 3 asymmetric dimethylation (H4R3Me2a) at their chromatin loci...

Significance of CCN2 expression in bovine preimplantation development.

Akizawa(H),Yanagawa(Y),Nagano(M),Bai(H),Taka… Anim Sci J 2019-01-00

...TEAD4 is required for proper TE differentiation in bovine blastocysts; however, the function of CCN2 during early embryo...

An EBNA1-YAP signaling axis drives immune escape through CD276 in EBV-associate…

Huang(B),Liu(M),Duan(Y),Guo(J),Wang(Z),Dou(Y… Cell Death Dis 2025-12-19

...TEAD4 chromatin occupancy at CD276 regulatory regions leads to its transcriptional upregulation in EBVaGC, driven by EBN...

Enhancer Reprogramming within Pre-existing Topologically Associated Domains Pro…

Qiao(Y),Wang(Z),Tan(F),Chen(J),Lin(J),Yang(J… Mol Ther 2020-00-02

...TEAD4 forms a complex with SMAD2/3 to mediate TGF-β signaling-triggered mesenchymal enhancer reprogramming. Together, ou...

Regulatory Master Genes Identification and Drug Repositioning by Integrative mR…

Fang(J),Pan(Z),Yu(H),Yang(S),Hu(X),Lu(X),Li(… Front Pharmacol 2020-00-00

...TEAD4 was predicted as a key modulator in protein-protein interaction (PPI) network. Weighted correlation network analys...

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