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Targeting SOX17 in human embryonic stem cells creates unique strategies for iso…

Wang(Pei),Rodriguez(Ryan T),Wang(Jing),Ghoda… Cell Stem Cell 2011-08-24

...SOX17 locus, a postulated marker of human endoderm. FACS purification and gene expression profiling confirmed that SOX17...

Biochemical and morphological effects of hypoxic environment on human embryonic…

Lim(Hee-Joung),Han(Jiyou),Woo(Dong-Hun),Kim(… Mol Cells 2011-06-20

...Sox17, AFP, and GATA4 on the EB periphery. Our data suggest that mild hypoxia facilitates the slow mitotic division of h...

Activation of FGFR(IIIc) isoforms promotes activin-induced mesendoderm developm…

Peterslund(Janny M L),Serup(Palle) Stem Cell Res 2011-08-12

...Sox17 in activin-induced EpCAM(+) cells. In contrast, ligands specifically activating FGFR(III)b isoforms have no effect...

Differentiation of human embryonic stem cells into pancreatic endoderm in patte…

Van Hoof(Dennis),Mendelsohn(Adam D),Seerke(R… Stem Cell Res 2011-08-12

...SOX17-positive/SOX7-negative definitive endoderm, after which many clusters released and formed uniformly sized three-di...

Sox17 regulates proliferation and cell cycle during gastric cancer progression.

Ye(Yan-Wei),Wu(Jiang-Hong),Wang(Chun-Meng),Z… Cancer Lett 2011-07-28

...Sox17 expression were low in gastric cancer tissues as compared to normal tissue (P=0.013). Knockdown of Sox17 by Sox17-...

Differentially expressed genes in Men1 knockout and wild‑type embryoid bodies f…

Zhang(Hong-Li),Li(Wen-Yi),Zhang(Cui-Ping),Zh… Mol Med Rep 2011-07-12

...SOX17, FOXA2 and NKX2.2 were found to be differentially expressed between the two embryoid bodies. Additionally, the gen...

Conversion of Sox17 into a pluripotency reprogramming factor by reengineering i…

Jauch(Ralf),Aksoy(Irene),Hutchins(Andrew Pau… Stem Cells 2011-09-13

...Sox17, despite binding to similar DNA sequences, cannot. Here, we show that Sox2 and Sox17 exhibit inverse heterodimeriz...

CD133 is a marker of gland-forming cells in gastric tumors and Sox17 is involve…

Fukamachi(Hiroshi),Shimada(Shu),Ito(Kosei),I… Cancer Sci 2011-08-26

...Sox17, a tumor suppressor in gastric carcinogenesis. Forced expression of SOX17 induced expression of CD133 in CD133(-) ...

p53-dependent regulation of growth, epithelial-mesenchymal transition and stemn…

Pinho(Andreia V),Rooman(Ilse),Real(Francisco… Cell Cycle 2011-08-31

...Sox17, and the stem cell markers c-myc, Bmi1 and Klf4. Cultures from p53(+/-) mice display intermediate levels of the tr...

Intracranial ectopic pancreatic tissue.

Heller(R Scott),Tsugu(Hitoshi),Nabeshima(Kaz… Islets 2011-03-31

...Sox17 had a weak staining in some areas of the pancreatic tissue but was much less widely expressed than FoxA2. The tumo...

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