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Association of subcellular localization of TEAD transcription factors with outc…

Drexler(R),Fahy(R),Küchler(M),Wagner(KC),Ree… Pancreatology 2021-01-00

...TEAD4 was evaluated with the immunoreactive score (IRS) by immunohistochemistry (IHC) using paraffin-embedded tissue. Re...

TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant…

Fujii(M),Toyoda(T),Nakanishi(H),Yatabe(Y),Sa… J Exp Med 2012-03-12

...TEAD4-Smad3-p300 complex on the CTGF promoter. Knocking down CTGF expression in MM cells prolonged the survival of xenog...

Convergent signaling in the regulation of connective tissue growth factor in ma…

Fujii(M),Nakanishi(H),Toyoda(T),Tanaka(I),Ko… Cell Cycle 2012-09-15

...TEAD4-Smad3-p300 complex on the specific CTGF promoter site with an adjacent TEAD and Smad binding motif is a critical a...

Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung can…

Adi Harel(S),Bossel Ben-Moshe(N),Aylon(Y),Bu… Cell Death Differ 2015-08-00

...TEAD4 mRNA was confirmed as a direct target of miR-512; likewise, miR-373 was found to target RelA and PIK3CA mRNA direc...

Novel Allosteric Effectors Targeting Human Transcription Factor TEAD.

Ibrahim(MT),Verkhivker(GM),Misra(J),Tao(P) Int J Mol Sci 2023-05-19

...TEAD4 and YAP1 domains indicated by the relative free energy perturbation to original molecules. Phe229, Thr332, Ile374,...

Nucleoporin37 may play a role in early embryo development in human and mice.

Peng(Y),Shen(J),Gao(Y),Dai(W),Liang(S),Chen(… Mol Hum Reprod 2022-00-27

...TEAD4) and NUP37. Furthermore, Nup37 gene knockdown reduced the nuclear import of YAP1 and down-regulated the expression...

Metformin: A promising clinical therapeutical approach for BPH treatment via in…

Yang(T),Yuan(J),Peng(Y),Pang(J),Qiu(Z),Chen(… J Pharm Anal 2024-01-00

...TEAD4) heterodimers. Met's anti-proliferative effects were blocked by AMPK inhibitor or YAP1 overexpression in DHT-cultu...

USP7 upregulated by TGF-β1 promotes ferroptosis via inhibiting LATS1-YAP axis i…

Lv(H),Yu(J),Qian(X),Shu(J),Qian(Q),Shen(L),S… iScience 2024-06-21

...TEAD4 to GPX4/SLC7A11 promoters. Furthermore, large tumor suppressor kinase 1 (LATS1) knockdown resulted in YAP expressi...

Targeted degradation of specific TEAD paralogs by small molecule degraders.

Chen(H),Gridnev(A),Schlamowitz(N),Hu(W),Dey(… Heliyon 2024-09-30

...TEAD4 at higher doses. Proteomic analysis of >6000 proteins confirmed their highly selective TEAD1 and TEAD3 degradation...

Super-Enhancers in Placental Development and Diseases.

Rosario(GX),Brown(S),Karmakar(S),Rumi(MAK),N… J Dev Biol 2025-04-09

...TEAD4, along with their binding sites and cis-regulatory elements, have been studied for their roles in trophoblast cell...

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