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PLZF regulates Pbx1 transcription and Pbx1-HoxC8 complex leads to androgen-inde…

Kikugawa(Tadahiko),Kinugasa(Yumi),Shiraishi(… Prostate 2006-07-18

...Pbx1 expression. Immunoprecipitation of Pbx1 in DU145 cells revealed a Pbx1-HoxC8 heterocomplex. siRNAs for Pbx1 and Hox...

Activin regulation of the follicle-stimulating hormone beta-subunit gene involv…

Bailey(Janice S),Rave-Harel(Naama),McGillivr… Mol Endocrinol 2005-03-17

...Pbx1 and Prep1. Using glutathione S-transferase interaction assays, we demonstrate that Pbx1 and Prep1 interact with Sma...

Expression of progenitor cell markers during expansion of sorted human pancreat…

Bouckenooghe(Thomas),Vandewalle(Brigitte),Mo… Gene Expr 2005-06-16

...PBX1, a homeodomain protein that can bind as a heterodimer with PDX1 and could switch the nature of its transcriptional ...

MyoD targets chromatin remodeling complexes to the myogenin locus prior to form…

de la Serna(Ivana L),Ohkawa(Yasuyuki),Berkes… Mol Cell Biol 2005-06-14

...Pbx1, which cooperates with MyoD to stimulate myogenin expression, is constitutively bound to the myogenin promoter in a...

A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny.

Brendolan(Andrea),Ferretti(Elisabetta),Salsi… Development 2005-09-08

...Pbx1 homozygous mutant (-/-) embryos, implicating the TALE homeoprotein Pbx1 in splenic cell specification. Pbx1 and Hox...

Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the…

Mazieres(Julien),You(Liang),He(Biao),Xu(Zhid… Oncogene 2005-09-01

...Pbx1 that promotes transformation and leukemogenesis. Wnt16 has been shown to be targeted by E2A-Pbx1. We performed a di...

Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells.

Feldhahn(Niklas),Río(Paula),Soh(Bonaventure … Proc Natl Acad Sci U S A 2005-11-09

...PBX1, MLL-AF4, TEL-AML1, or TEL-PDGFRB gene rearrangement. Although somatic mutations of the BTK gene are rare in B cell...

Evaluation of sequence variants in the pre-B cell leukemia transcription factor…

Wang(Hua),Chu(Winston),Wang(Xiaoqin),Zhang(Z… Mol Genet Metab 2005-12-09

Pre-B cell leukemia transcription factor 1 (PBX1) encodes a homeodomain containing protein that is essential for pancrea...

Hoxb1 enhancer and control of rhombomere 4 expression: complex interplay betwee…

Ferretti(Elisabetta),Cambronero(Francisco),T… Mol Cell Biol 2005-12-05

...Pbx1 (PM1, PM2, and PM3) and Pbx1-Hoxb1 (R1 and R3) binding sites that cooperate to modulate and spatially restrict the ...

Privileged scaffolds for blocking protein-protein interactions: 1,4-disubstitut…

Ji(Tao),Lee(Madison),Pruitt(Steven C),Hangau… Bioorg Med Chem Lett 2005-04-12

...PBX1/DNA transcription factor complex, were used to identify 1,4-disubstituted naphthalenes as potential antagonists. An...

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