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The Epigenetic Factor PHF13 Governs Trophoblast Stemness and Differentiation.

Liu(S),Liu(L),Meng(J),Sadovsky(E),Huang(K),S… bioRxiv 2026-03-17

...TEAD4. Integrated genomic analyses further revealed that PHF13 target genes comprise a gene regulatory network that main...

Enhancer Reprogramming within Pre-existing Topologically Associated Domains Pro…

Qiao(Y),Wang(Z),Tan(F),Chen(J),Lin(J),Yang(J… Mol Ther 2020-00-02

...TEAD4 forms a complex with SMAD2/3 to mediate TGF-β signaling-triggered mesenchymal enhancer reprogramming. Together, ou...

Hypomethylation Causes MIR21 Overexpression in Tumors.

Lu(J),Tan(T),Zhu(L),Dong(H),Xian(R) Mol Ther Oncolytics 2020-09-25

...TEAD4, which were co-expressed with miR-21 in tumors. These observations identified that gene hypomethylation regulated ...

Analysis of transcription factors in accessible open chromatin in the 18-trisom…

Qiu(XF),Tang(D),Yu(HY),Liao(QY),Hu(ZY),Zhou(… Yi Chuan 2021-01-20

...TEAD4, Twist2) were confirmed using real-time quantitative fluorescence PCR. In conjunction with information from the li...

Regulatory Master Genes Identification and Drug Repositioning by Integrative mR…

Fang(J),Pan(Z),Yu(H),Yang(S),Hu(X),Lu(X),Li(… Front Pharmacol 2020-00-00

...TEAD4 was predicted as a key modulator in protein-protein interaction (PPI) network. Weighted correlation network analys...

Two Cohorts, One Network: Consensus Master Regulators Orchestrating Papillary T…

Tapia-Carrillo(D),Zambada-Moreno(O),Hernánde… Int J Mol Sci 2025-11-20

...TEAD4 as upstream regulators controlling other TMRs. Functional enrichment revealed activation of NOTCH, MAPK, PI3K, and...

Gancao Xiexin decoction attenuated experimental colitis through suppressing ACS…

Pan(Z),Gan(C),Zhi(S),Yang(Y),Zhang(Y),Li(L),… J Ethnopharmacol 2025-03-26

...TEAD4 functions as an upstream transcription factor for ACSL4, we combined GCXXD and Py-60, a YAP agonist in the treatme...

Loss of Anks6 leads to YAP deficiency and liver abnormalities.

Airik(M),Schüler(M),McCourt(B),Weiss(AC),Her… Hum Mol Genet 2020-00-04

...TEAD4 and promoting their transcriptional activity. Together, this study reveals a novel function for ANKS6 in regulatin...

Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cell…

Jaju Bhattad(G),Jeyarajah(MJ),McGill(MG),Dum… Cell Death Dis 2020-00-04

...TEAD4, TP63, OVOL1, CGB), as well as near genes with novel regulatory roles in trophoblast development and function, suc...

PI3K/AKT/β-Catenin Signaling Regulates Vestigial-Like 1 Which Predicts Poor Pro…

Kim(BK),Cheong(JH),Im(JY),Ban(HS),Kim(SK),Ka… Cancers (Basel) 2019-12-03

...TEAD4 complex, a component of the transcription factor. Taken together, PI3K/AKT/β-catenin signaling regulates the trans...

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