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Insights into the molecular mechanism of action of Celastraceae sesquiterpenes …

Muñoz-Martínez(F),Reyes(CP),Pérez-Lomas(AL),… Biochim Biophys Acta 2006-01-00

...Pgp, or whether they affect Pgp expression as well as its activity, or about the location of their binding site within t...

Radioligands targeting P-glycoprotein and other drug efflux proteins at the blo…

Wanek(Thomas),Mairinger(Severin),Langer(Oliv… J Labelled Comp Radiopharm 2014-07-16

...Pgp. Pgp imaging probes can be classified as radiolabeled substrates or inhibitors. The radiolabeled substrates (R)-[(11...

The matrikine N-acetylated proline-glycine-proline induces premature senescence…

Feng(Chencheng),Zhang(Yang),Yang(Minghui),La… Biochim Biophys Acta 0000-00-00

...PGP induced premature senescence of NP cells by binding to CXCR1. N-Ac-PGP induced DNA damage and reactive oxygen specie...

Rolipram-Loaded Polymeric Micelle Nanoparticle Reduces Secondary Injury after R…

Macks(C),Gwak(SJ),Lynn(M),Lee(JS) J Neurotrauma 2018-00-01

...PgP), for combinatorial delivery of therapeutic nucleic acids and drugs for SCI repair. In this study, we evaluated PgP ...

Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibros…

Turnbull(AR),Pyle(CJ),Patel(DF),Jackson(PL),… J Cyst Fibros 2020-00-00

...PGP, MMP-9, PE and LTA4H were assessed. Whilst PGP was present in all but one of the older CF children tested, it was ab...

The pelvic girdle pain deadlock: 1. Would 'deconstruction' help?

Meijer(OG),Hu(H),Wu(WH),Prins(MR) Musculoskelet Sci Pract 2020-00-00

...PGP', around 2005, and then continued problems in really understanding PGP's nature and causes. We propose to engage in ...

The collagen-breakdown product N-acetyl-Proline-Glycine-Proline (N-alpha-PGP) d…

de Kruijf(Petra),Lim(Herman D),Overbeek(Sask… Eur J Pharmacol 2010-12-07

...PGP) attracts neutrophils. In a recent article (Weathington et al., 2006) it was suggested that N-alpha-PGP exerts its e...

Haemonchus contortus P-glycoproteins interact with host eosinophil granules: a …

Issouf(Mohamed),Guégnard(Fabrice),Koch(Chris… PLoS One 2014-10-20

...Pgp genes, Hco-pgp-3, Hco-pgp-9.2, Hco-pgp-11 and, Hco-pgp-16 were specifically up-regulated in parasitic life stages su...

P-glycoprotein enhances radiation-induced apoptotic cell death through the regu…

Tsang(Tsun Yee),Tang(Wan Yee),Chan(Judy Yuet… Apoptosis 2011-08-16

...Pgp effect on miR-16/Bcl-2 was suppressed by Pgp blocker verapamil indicating the importance of the efflux of Pgp substr...

N-acetylated Proline-Glycine-Proline induced G-protein dependent chemotaxis of …

Overbeek(Saskia A),Henricks(Paul A J),Srienc… Eur J Pharmacol 2012-01-19

...PGP). In this study, we investigated in more detail the mechanism of action of N-ac-PGP in neutrophilic inflammation. N-...

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