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TGF-β1, EGF and FGF4 synergistically induce differentiation of the seminoma cel…

Nettersheim(D),Gillis(AJ),Looijenga(LH),Scho… Int J Androl 2011-08-00

...TEAD4 and YAP1. These molecules have been described to trigger extra-embryonic fate determination in the murine system. ...

Myogenic differential methylation: diverse associations with chromatin structur…

Chandra(S),Baribault(C),Lacey(M),Ehrlich(M) Biology (Basel) 2014-06-19

...TEAD4 had myogenic hypomethylation in intronic subregions displaying enhancer-type or transcription-type chromatin in th...

Vestigial-like family member 3 stimulates cell motility by inducing high-mobili…

Hori(N),Takakura(Y),Sugino(A),Iwasawa(S),Nom… J Cell Mol Med 2022-00-00

...TEAD4 complex, and HMGA2 knockdown repressed EMT-like phenotypic changes in VGLL3-expressing cells. VGLL3-dependent phen...

USP49 mediates tumor progression and poor prognosis through a YAP1-dependent fe…

Liu(Z),Li(J),Ding(Y),Ma(M),Chen(J),Lei(W),Li… Oncogene 2022-00-00

...TEAD4 complex, which formed a positive feedback loop with YAP1 to promote the malignant progression of GC cells. Finally...

Integrated Multi-Tissue Transcriptomics Reveals Antagonistic Pleiotropy in Agin…

Salihoglu(R),Can(Ş),Dandekar(T),Bencurova(E) Comput Struct Biotechnol J None

...TEAD4 as candidate resilience-associated regulators, showing directionally opposite patterns relative to immune- and dev...

Elastic modulus of hydrogel regulates osteogenic differentiation via liquid-liq…

Tan(K),Yang(Q),Han(Y),Zhuang(Z),Zhao(Y),Guo(… J Biomed Mater Res A 2023-00-00

...TEAD4, but not RUNX2 into the condensates. In vivo, we also found that hBMSCs in high-elastic-modulus GelMA was more apt...

Verteporfin induces apoptosis and eliminates cancer stem-like cells in uveal me…

Ma(YW),Liu(YZ),Pan(JX) Am J Cancer Res 2016-00-00

...TEAD4 in UM cells and decreased the expression of YAP targeted downstream genes. Verteporfin treatment decreased the cyt...

Employing unnatural promiscuity of sortase to construct peptide macrocycle libr…

Zhang(YN),Wan(XC),Tang(Y),Chen(Y),Zheng(FH),… Chem Sci 2024-06-26

...TEAD4 with a nanomolar KD value (63.9 nM). Importantly, the binding affinity of the bicyclic peptide ligand is 102-fold ...

METTL3 shapes m6A epitranscriptomic landscape for successful human placentation.

Kumar(RP),Kumar(R),Ganguly(A),Ghosh(A),Ray(S… bioRxiv 2024-07-13

...TEAD4, WWTR1, YAP1, TFAP2C and ASCL2, and loss of METTL3 leads to depletion of mRNA molecules of these critical regulato...

Induction of the TEAD Coactivator VGLL1 by Estrogen Receptor-Targeted Therapy D…

Gemma(C),Lai(CF),Singh(AK),Belfiore(A),Portm… Cancer Res 2024-12-16

...TEAD4 interaction inhibited VGLL1/TEAD-induced transcriptional programs to prevent the growth of resistant cells. EGFR w...

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