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Adipose-derived stromal cells protect intervertebral disc cells in compressio...

Sun(Zhen),Luo(Beier),Liu(Zhi-Heng),Samartz... Int J Biol Sci 2015-09-28

...COL2A1 and ACAN), tissue inhibitors of metalloproteinases (TIMPs) genes (TIMP-1 and TIMP-2) and cytokeratin 8 (CK8) prot...

MicroRNAs: Important Epigenetic Regulators in Osteoarthritis.

Trzeciak(Tomasz),Czarny-Ratajczak(Malwina) Curr Genomics 2015-01-19

...COL2A1 gene, encoding collagen type II, which is the most abundant structural protein of the cartilage, is silenced by m...

Gradient Fractionated Separation of Chondrogenically Committed Cells Derived ...

Joergensen(Natasja Leth),Gabrielsen(Anette... Biores Open Access 2015-08-28

...COL2A1 and the ratio COL2A1:COL1A1 were significantly lower. Additionally, toluidine blue pH 4 stains of pellet cultures...

AMP-activated protein kinase (AMPK) activity negatively regulates chondrogeni...

Bandow(Kenjiro),Kusuyama(Joji),Kakimoto(Ky... Bone 2015-11-24

...col2a1 and aggrecan core protein (acp). Thus, chondrocyte differentiation is functionally associated with decreased AMPK...

Identification of SCAN domain zinc-finger gene ZNF449 as a novel factor of ch...

Okada(Keita),Fukai(Atsushi),Mori(Daisuke),... PLoS One 2015-09-04

...COL2A1. Zfp449 was expressed in mesenchyme-derived tissues including cartilage, calvaria, muscle and tendon, as well as ...

The mouse MC13 mutant is a novel ENU mutation in collagen type II, alpha 1.

Cionni(Megan),Menke(Chelsea),Stottmann(Rol... PLoS One 2015-11-30

...Col2a1). Col2a1 has previously been studied in the mouse and our mutant phenotype closely resembles mutations made in th...

Comparison of growth factor adsorbed scaffold and conventional scaffold with ...

Klangjorhor(Jeerawan),Phitak(Thanyaluck),P... BMC Biotechnol 2015-10-05

...COL2A1 (1.83 fold). Remarkably, over the 21 days of cultivation, HA + TGF-β3 adsorbed scaffolds promoted the extracellul...

MicroRNA expression profiles in human adipose-derived stem cells during chond...

Yang(Zhen),Hao(Jie),Hu(Zhen-Ming) Int J Mol Med 2015-10-05

...Col2A1), collagen, type X, alpha 1 (Col10A1) and aggrecan. Furthermore, it was confirmed that miR‑490‑5p directly target...

Monotropein exerts protective effects against IL-1β-induced apoptosis and cat...

Wang(Feng),Wu(Longhuo),Li(Linfu),Chen(Siyi... Int Immunopharmacol 2015-07-28

...COL2A1 was increased. Taken together, these findings suggested that monotropein exerted anti-apoptosis and anti-cataboli...

Clinical Outcome 3 Years After Autologous Chondrocyte Implantation Does Not C...

Stenberg(Johan),de Windt(Tommy S),Synnergr... Orthop J Sports Med 2015-11-04

...COL2A1], bone morphogenic protein 2 [BMP2], fibroblast growth factor receptor 3 [FGFR3], aggrecan [ACAN], CD44, and acti...

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