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The proliferative and the antifibrotic side of PAX2 in tubular repair.

Wessely(O),Shankland(SJ) Kidney Int 2022-00-00

...Pax2 in PTECs is required for their regenerative proliferation and repair. However, a loss-of-function study now shows t...

Mutation of PAX2 in two siblings with renal-coloboma syndrome.

Sanyanusin(P),McNoe(LA),Sullivan(MJ),Weaver(… Hum Mol Genet 1995-11-00

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PAX immunoreactivity in poorly differentiated small round cell tumors of childh…

Fan(Rong) Fetal Pediatr Pathol 2015-05-11

...PAX2, PAX5 and PAX8) in poorly differentiated small round cell tumors of childhood for possible useful diagnostic applic...

A wide spectrum of phenotypes in a family with renal coloboma syndrome caused b…

Adam(Jennifer),Browning(Andrew C),Vaideanu(D… Clin Kidney J 2016-06-13

...PAX2. We present three generations of a family with a PAX2 mutation who showed variable eye and renal phenotypes. Renal ...

SNP Variants in RET and PAX2 and Their Possible Contribution to the Primary Hyp…

Coulter-Mackie(Marion B) Biochem Genet 2016-01-11

...PAX2 genes associated with reduced nephron number. The frequencies of these SNPs were compared in PH1-affected DNA sampl...

Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establi…

Naiman(N),Fujioka(K),Fujino(M),Valerius(MT),… Dev Cell 2017-00-22

...Pax2 fail to differentiate into nephron cells but can switch fates into renal interstitium-like cell types. These data s...

New PAX2 heterozygous mutation in a child with chronic kidney disease: a case r…

Zhang(L),Zhai(SB),Zhao(LY),Zhang(Y),Sun(BC),… BMC Nephrol 2018-00-21

We herein report a 3-year-old boy presented with chronic kidney disease (CKD) due to PAX2 missense mutation (C to G tran...

Rapid identification of PAX2/5/8 direct downstream targets in the otic vesicle …

Ramialison(Mirana),Bajoghli(Baubak),Aghaalla… Genome Biol 2010-03-31

The pax2/5/8 genes belonging to the PAX family of transcription factors are key developmental regulators that are involv...

Integration of an abdominal Hox complex with Pax2 yields cell-specific EGF secr…

Li-Kroeger(David),Cook(Tiffany A),Gebelein(B… Development 2012-05-31

...Pax2. Last, we show that Abdominal-A uses both Pax2-dependent and Pax2-independent mechanisms to stimulate rhomboid CRM ...

Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 …

Gao(Xiaobo),Chen(Xing),Taglienti(Mary),Rumba… Development 2007-08-17

...Pax2 in the mesenchyme of the early kidney, and for Pax2 to stimulate expression of Gdnf. However, once Gdnf stimulates ...

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