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Prevention of autoimmune gastritis in mice requires extra-thymic T-cell deletio…

Read(Simon),Hogan(Thea V),Zwar(Tricia D),Gle… Gastroenterology 2007-09-06

...Atp4a and Atp4b (H(+)/K(+) ATPase). Here, we have elucidated events that result in immunological tolerance to the H(+)/K...

Identification, genome mapping, and CTCF binding of potential insulators within…

Akopov(Sergey B),Ruda(Vera M),Batrak(Vera V)… Mamm Genome 2006-12-07

...ATP4A) and amyloid beta (A4) precursor-like protein 1 (APLP1) within the locus studied were found to be flanked by insul...

Dietary acidification enhances phosphorus digestibility but decreases H+/K+-ATP…

Sugiura(Shozo H),Roy(Prabir K),Ferraris(Rona… J Exp Biol 2006-12-13

...ATP4A mRNA had > or = 95% amino acid homology with mammalian, Xenopus and flounder ATP4A. Although ATP4A seems highly co...

Gastric achlorhydria in H/K-ATPase-deficient (Atp4a(-/-)) mice causes severe hy…

Judd(Louise M),Andringa(Anastasia),Rubio(Car… J Gastroenterol Hepatol 2006-06-13

...Atp4a(-/-) and Atp4a(+/+) mice, paired for age and gender, were examined at 3, 8, 12 and 20 months for histopathology, a...

Tissue specificity of methylation of cytosines in regulatory regions of four ge…

Chalaya(T V),Akopov(S B),Nikolaev(L G),Sverd… Biochemistry (Mosc) 2006-09-29

...ATP4A), there was no correlation between methylation and expression. It is possible that methylation provides some basal...

Stomachs of mice lacking the gastric H,K-ATPase alpha -subunit have achlorhydri…

Spicer(Z),Miller(M L),Andringa(A),Riddle(T M… J Biol Chem 2000-08-16

...Atp4a(-/-)) mice appeared healthy and exhibited normal systemic electrolyte and acid-base status but were achlorhydric a...

Chromosomal assignment of 11 loci in the rat by mouse-rat somatic hybrids and l…

Deng(A Y),Gu(L),Rapp(J P),Szpirer(C),Szpirer… Mamm Genome 1995-03-31

...Atp4a), Class I alcohol dehydrogenase (Adh), and aldolase C (Aldoc) were localized to Chrs 1, 2, and 10 respectively, an...

Genes encoding the H,K-ATPase alpha and Na,K-ATPase alpha 3 subunits are linked…

Malo(D),Gros(P),Bergmann(A),Trask(B),Mohrenw… Mamm Genome 1994-02-14

...Atp4a) and human (ATP4A) genes encoding the H,K-ATPase alpha subunit. Linkage analysis in recombinant inbred (BXD) strai...

Does long-term profound inhibition of gastric acid secretion increase the risk …

Waldum(Helge L),Hauso(Øyvind),Brenna(Eiliv),… Scand J Gastroenterol 0000-00-00

...ATP4A gene clearly shows that hypergastrinemia alone also is sufficient to induce ECL cell neoplasia in man. The present...

Benzimidazole covalent probes and the gastric H(+)/K(+)-ATPase as a model syste…

Paresi(Chelsea J),Liu(Qi),Li(Yue-Ming) Mol Biosyst 0000-00-00

...ATP4A. This study validates the use of chemical probes for target identification and illustrates the superior efficiency...

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