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Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the diet...

Vlaming(Maria L H),Teunissen(Sebastiaan F)... Mol Pharmacol 2014-04-01

...Bcrp1 and Mdr1a limited PhIP brain accumulation. In Bcrp1;Mrp2;Mrp3(-/-), but not Bcrp1;Mdr1a/b;Mrp(-/-) mice, the carci...

Stage-specific embryonic antigen-4 is expressed in basaloid lung cancer and a...

Gottschling(Sandra),Jensen(Katrin),Warth(A... Eur Respir J 2013-09-30

...BCRP1), and to prognosis. SSEA-4 was positive in 37% of the specimens and showed no association with clinico-pathologica...

Breast cancer resistance protein (ABCG2) determines distribution of genistein...

Yang(Zhen),Zhu(Wei),Gao(Song),Yin(Taijun),... Drug Metab Dispos 2013-02-14

...Bcrp1(-/-) mice. In contrast, the intestinal and biliary excretion of genistein conjugates significantly decreased in Bc...

[Study of the invasiveness and tumour formation of Bcrp1(+) HeLa cervical can...

Zhang(Song-ling),Yu(Xiao-wei),Wang(Jian-li... Zhonghua Fu Chan Ke Za Zhi 2013-06-24

...Bcrp1(+) groups than those in the Bcrp1(-) groups (P < 0.05).,Bcrp1(+) HeLa cell have the greater capacity of invasive a...

Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and...

Kretschmer(Nadine),Rinner(Beate),Stuendl(N... Planta Med 2013-05-03

...BCRP1) was examined using real-time RT-PCR. The expressions of ABCB1/MDR1 and ABCG2/BCRP1 in liposarcoma and synovial sa...

Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier ...

Bauer(Florian),Wanek(Thomas),Mairinger(Sev... Eur J Pharmacol 2013-04-17

...Bcrp1((-/-)) mice and significantly, i.e. 4.7-fold (P<0.01), higher brain uptake, relative to wild-type animals, in Mdr1...

Co-administration strategy to enhance brain accumulation of vandetanib by mod...

Minocha(Mukul),Khurana(Varun),Qin(Bin),Pal... Int J Pharm 2013-01-04

...Bcrp1) in vitro and in vivo (ii) to study the modulation of P-gp and BCRP mediated efflux of vandetanib with specific tr...

Conditionally replicative adenovirus-based mda-7/IL-24 expression enhances se...

Xu(Jing),Mo(Yiwo),Wang(Xiaoyun),Liu(Jun),Z... J Gastroenterol 2013-08-05

...BCRP1) expression. Consistently, 5-fluorouracil and doxorubicin induced more apoptosis in AdBB-IL24-infected colon cance...

Enhanced brain accumulation of pazopanib by modulating P-gp and Bcrp1 mediate...

Minocha(Mukul),Khurana(Varun),Qin(Bin),Pal... Int J Pharm 2013-01-16

...Bcrp1 (by Ko143) alone did not significantly alter pazopanib brain accumulation. However, dual P-gp/Bcrp1 inhibition by ...

Assessment and modulation of forsythiaside absorption with MDCKII cells and v...

Li(Yun-Xia),Zhang(Ruo-Qi),Peng(Cheng) Eur J Drug Metab Pharmacokinet 2013-04-24

...Bcrp1, respectively. The efflux ratios in MRP2 and Bcrp1 transfected cell lines were greatly decreased in the presence o...

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