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Modulating intracellular calcium dynamics with alkaloids: A novel strategy ag...

Niğdelioğlu Dolanbay(S) Toxicol Res (Camb) 2025-08-00

...CaMK2A, PMCA (ATP2B1), SERCA (ATP2A1), RyR1, and IP3R (ITPR1), as confirmed by ELISA and Western Blot analysis. Protein-...

Neuronal PAC1 deletion impairs structural plasticity.

Jansen(MI),Hrncir(H),MacKenzie-Graham(A),W... Life Sci 2025-10-01

...Camk2a-expressing excitatory neurons. The model was crossed with Thy1-YFP and Thy1-mitoCFP reporter lines to enable high...

Transcriptome profiling reveals major structural genes, transcription factors...

Ben(X),Zhang(P),Li(C),Zou(Q),Cai(Y),Wang(S... BMC Neurol 2025-07-12

...CAMK2A, CAMK2B, and CAMK2D as key genes potentially involved in tropical refractory epilepsy. Moreover, our comparison o...

Construction and immunohistochemical validation of a necroptosis-related prog...

Wang(T),Ding(F),Sun(K) Front Genet 2025-00-00

...CAMK2A, CHMP4C, IL33, IRF9, and TRAF5). Based on these genes, we developed a robust prognostic model that can stratify p...

Eleganolone, a diterpene isolated from seaweed Bifurcaria bifurcata (Phaeophy...

Martínez(MA),Lopez-Torres(B),Maximiliano(J... Eur J Pharmacol 2025-09-15

...CAMK2A, WNT5A, WNT7A) pathways in SH-SY5Y cells exposed to oxidative stressor tert-BOOH. These findings suggest that ele...

Reelin signaling pathway genotypes and Alzheimer disease in a Spanish populat...

Bufill(Enric),Roura-Poch(Pere),Sala-Matave... Alzheimer Dis Assoc Disord 2016-02-08

...CAMK2A (rs3756577 and rs3822606) and AD or MCI was found. A significant association also was found between the GG genoty...

Reversal of age-associated cognitive deficits is accompanied by increased pla...

Li(Yan),Abdourahman(Aicha),Tamm(Joseph A),... Pharmacol Biochem Behav 2016-04-12

...Camk2a, Arc, Shank1, Nlgn2, and Rab3a). Neither drug reversed the age-associated decrease in stem cell proliferation. Hi...

Cre recombinase activity is inhibited in vivo but not ex vivo by a mutation i...

Arguello(Tania),Moraes(Carlos T) Genesis 2016-09-04

...Camk2a-cre) and myosin light polypeptide 1 (Myl1-cre). Surprisingly, transient transfection of a plasmid expressing cre ...

An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal f...

Walker(Adam K),Tripathy(Kalyan),Restrepo(C... Hum Mol Genet 2016-09-20

...Camk2a-controlled doxycycline-suppressible expression of a TDP-43 CTF (amino acids 208-414, designated 208 TDP-43 CTF), ...

Effect of nicotinamide mononucleotide on brain mitochondrial respiratory defi...

Long(Aaron N),Owens(Katrina),Schlappal(Ann... BMC Neurol 2016-04-07

...CaMK2a-mito/eYFP), were administered NMN.,Mitochondrial oxygen consumption rates were examined in N2A neuroblastoma cell...

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