Parry(Marina),Rose-Zerilli(Matthew J J),Gi... PLoS One 2015-03-30

...FAT4, FBXO11, PLA2G4D, TRRAP and USH2A. By integrating our WES and CN data we identified three mutated putative candidat...

Bagherie-Lachidan(Mazdak),Reginensi(Antoin... Development 2015-10-23

...FAT4 acts non-autonomously in the renal stroma to control nephron progenitors. We show that loss of Yap from the CM in F...

Mao(Yaopan),Francis-West(Philippa),Irvine(... Development 2015-10-23

...Fat4 mutants implicates Dchs1 in Fat4-dependent stroma-to-cap mesenchyme signaling. Antibody staining of genetic mosaics...

Sugiyama(Yuki),Shelley(Elizabeth J),Badoue... Invest Ophthalmol Vis Sci 2015-09-03

...Fat4 in eye development was assessed. Lens phenotypes in Fat1 and 4 knockouts were also examined.,Fat1 and Fat4 mRNA exp...

Jung(Hae Yoen),Cho(Hyundeuk),Oh(Mee-Hye),L... J Gastric Cancer 2015-04-11

...FAT4, a candidate tumor suppressor gene, in cancer. FAT atypical cadherin 4 (FAT4) is a transmembrane receptor involved ...

Furukawa(Toru),Sakamoto(Hitomi),Takeuchi(S... Sci Rep 2015-11-25

...FAT4 showed somatic or germline missense mutations in 4 of 7 tumors. The germline FAT mutations were with loss of the wi...

Deng(Xiao-Lu),Yin(Fei),Zhang(Guo-Yuan),Dua... Zhongguo Dang Dai Er Ke Za Zhi 2015-04-30

...FAT4 have been found responsible for the syndrome in a part of patients. Diagnosis of the disease depends on the familia...

Badouel(Caroline),Zander(Mark A),Liscio(Ni... Development 2015-11-05

...Fat4 to regulate these processes. Proteomic analysis reveals that Fat1 and Fat4 bind different sets of actin-regulating ...

Tsukasaki(Yoshikazu),Miyazaki(Naoyuki),Mat... Proc Natl Acad Sci U S A 2015-04-14

...Fat4 and Dachsous1 ectodomains, however, revealed that, although their N-terminal regions exhibit a linear configuration...

Zakaria(Sana),Mao(Yaopan),Kuta(Anna),Ferre... Curr Biol 2015-09-10

...FAT4 and DCHS1, key components of Fat-PCP signaling, cause Van Maldergem syndrome, characterized by severe neuronal abno...