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Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acu...

Shah(Shilpan),Loghavi(Sanam),Garcia-Manero... J Hematol Oncol 2015-01-02

...FIP1L1-PDGFRA in chronic myelomonocytic leukemia (CMML). Herein, we present a case report of a patient in whom the FIP1L...

Idiopathic hypereosinophilic syndrome: a rare cause of erythroderma.

Mahajan(Vikram K),Singh(Ravinder),Mehta(Ka... J Dermatol Case Rep 2015-01-27

...FIP1L1-PDGFRA gene analysis were suggestive of lymphocytic HES. The patient was treated with hydroxycarbamide (1 g/day),...

F604S exchange in FIP1L1-PDGFRA enhances FIP1L1-PDGFRA protein stability via ...

Gorantla(S P),Zirlik(K),Reiter(A),Yu(C),Il... Leukemia 2015-11-05

...FIP1L1-PDGFRA stabilization, this explains the extended half-life of FIP1L1-PDGFRA/F604S. Interestingly, FIP1L1-PDGFRA/L...

[The hematological malignancies related to primary hypereosinophilia and thei...

Skonieczka(Katarzyna),Matiakowska(Karolina... Postepy Hig Med Dosw (Onlin... 2015-08-25

...FIP1L1-PDGFRA), specific for hypereosinophilia-associated diseases. In differential diagnosis of hypereosinophilia, the ...

Generalized Eruptive Histiocytosis Associated With FIP1L1-PDGFRA-Positive Chr...

Ziegler(Birgit),Peitsch(Wiebke K),Reiter(A... JAMA Dermatol 2015-09-21

...FIP1L1-PDGFRA-positive chronic eosinophilic leukemia. The patient was treated with imatinib and achieved complete clinic...

Refractory myeloid sarcoma with a FIP1L1-PDGFRA rearrangement detected by cli...

Mandelker(Diana),Dal Cin(Paola),Jacene(Hea... Exp Hematol Oncol 2015-10-12

...FIP1L1-PDGFRA rearrangement in his tumor. The patient was immediately placed on Imatinib therapy to which he responded, ...

The oncogenic FIP1L1-PDGFRα fusion protein displays skewed signaling properti...

Haan(Serge),Bahlawane(Christelle),Wang(Jia... JAKSTAT 2015-09-28

...FIP1L1-PDGFRα kinase exhibits a significantly different signaling pattern compared to its PDGFRα wild type counterpart. ...

KIT D816V and JAK2 V617F mutations are seen recurrently in hypereosinophilia ...

Schwaab(Juliana),Umbach(Roland),Metzgeroth... Am J Hematol 2015-11-03

...FIP1L1-PDGFRA (FP) fusion gene also for KIT D816V and JAK2 V617F mutations. Overall, 86 (20%) patients tested positive: ...

WATERSHED INFARCTION IN HYPEREOSINOPHILIC SYNDROME: A DIAGNOSTIC DILEMMA IN F...

Marton(Imelda),Pósfai(Éva),Annus(János Kri... Ideggyogy Sz 2015-08-18

...FIP1L1-PDGFR alpha-positive, hypereosinophilic syndrome (HES) is a new category of hematological entities. Various clini...

Complete and long-lasting cytologic and molecular remission of FIP1L1-PDGFRA-...

Barraco(Daniela),Carobolante(Francesca),Ca... Eur J Haematol 2015-01-06

...FIP1L1-PDGFRA-positive chronic myeloproliferative disorders with eosinophilia. However, the coexistence of FIP1L1-PDGFRA...

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