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Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating...

Pilati(Camilla),Letouzé(Eric),Nault(Jean-C... Cancer Cell 2014-07-23

...FRK mutations that induce constitutive kinase activity, STAT3 activation, and cell proliferation sensitive to Src inhibi...

Molecular contribution to cleft palate production in cleft lip mice.

Sasaki(Yasunori),Taya(Yuji),Saito(Kan),Fuj... Congenit Anom (Kyoto) 2014-12-09

...Frk) were linked in a gene network that associates with cell proliferation (cell cycle, MAPK, Wnt and Tgf beta pathways)...

Substantial roles of hexokinase and fructokinase in the effects of sugars on ...

Granot(David),Kelly(Gilor),Stein(Ofer),Dav... J Exp Bot 2014-10-07

...FRKs). These hexose-phosphorylating enzymes appear to coordinate sugar production with the abilities to absorb light, CO...

In silico identification of oncogenic potential of fyn-related kinase in hepa...

Chen(Jia-Shing),Hung(Wei-Shiang),Chan(Hsia... Bioinformatics 2013-08-12

...FRK expression and invasiveness, suggesting that FRK is a positive regulator of invasiveness in liver cancer cells.,Thes...

Hexose kinases and their role in sugar-sensing and plant development.

Granot(David),David-Schwartz(Rakefet),Kell... Front Plant Sci 2013-03-17

...FRKs. The emerging picture indicates that HXK and FRK enzymes found at specific intracellular locations play distinct ro...

FRK controls migration and invasion of human glioma cells by regulating JNK/c...

Zhou(Xiuping),Hua(Lei),Zhang(Weijian),Zhu(... J Neurooncol 2013-04-23

...FRK were significantly down-regulated in human primary glioma tissues. In addition, over-expression of FRK inhibited mig...

[Expressions of receptor tyrosine kinases mRNA and protein in carcinoma of bl...

Wen(Jin),Li(Han-zhong),Ji(Zhi-gang),Yan(We... Zhongguo Yi Xue Ke Xue Yuan... 2013-10-29

...FRK, Fyn, IGF-IR, Insulin R, Itk, JAK1, JAK3, and LCK were low-expressed.,Vascular endothelial growth factor/platelet-de...

Caveolin-1 as a potential high-risk prostate cancer biomarker.

Gumulec(Jaromir),Sochor(Jiri),Hlavna(Maria... Oncol Rep 2012-08-10

...FRK) and blue chromium peroxide (Cro) in 97 serum samples (82 prostate cancer patients and 15 controls). We ...

Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: ...

Montero(Juan Carlos),Seoane(Samuel),Ocaña(... Clin Cancer Res 2012-02-24

...FRK), and the receptor tyrosine kinases c-KIT, platelet-derived growth factor receptor (PDGFR) α and β, discoidin domain...

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-r...

Yu(Yi),Bhangale(Tushar R),Fagerness(Jesen)... Hum Mol Genet 2012-01-17

...FRK/COL10A1 [odds ratio (OR) 0.87; P = 1.1 × 10(-8)] and rs4711751 on 6p12 near VEGFA (OR 1.15; P = 8.7 × 10(-9)). In ad...

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