Long(Yan),Wang(Yubang),Ji(Guixiang),Yan(Li... PLoS One 2013-09-04

...Herc5 (hect domain and RLD 5 isoform 2) and Tyro3 (TYRO3 protein tyrosine kinase 3) were found down-regulated, while Sdh...

Ishizu(Akihiro),Tomaru(Utano),Murai(Taichi... PLoS One 2013-12-16

...HERC5, CCR1, CD36, MS4A4A, BIRC4BP, PLSCR1, DEFA1/DEFA3, DEFA4, and COL9A2 as the important genes that can predict the r...

Oudshoorn(Diede),van Boheemen(Sander),Sánc... PLoS One 2012-06-11

...HerC5 in mouse cells, suggesting that HerC6(-/-) mice may provide a feasible model to study the role of human HerC5 in a...

Durfee(Larissa A),Huibregtse(Jon M) Methods Mol Biol 2012-07-16

...Herc5, respectively, and these are all also induced at the transcriptional level by IFN-α/β. We recently showed that Her...

Woods(Matthew W),Kelly(Jenna N),Hattlmann(... Retrovirology 2012-01-30

...HERC5) that blocks a unique late stage of the HIV-1 life cycle.,HERC5 inhibited the replication of HIV-1 over multiple r...

Jiménez-Sousa(María Ángeles),Almansa(Raque... Enferm Infecc Microbiol Cli... 2012-01-23

...HERC5 and APOBEC3) than in non-responders (ISG15, IFI44L, IFI27, IRF7, USP18) in the first twelve weeks of treatment (P<...

Zhu(Zi-Xiang),Wei(Jian-Chao),Shi(Zi-Xue),W... Bing Du Xue Bao 2012-04-12

...HERC5 proteins, which are all essential for ISGylation. ISG15 and ISGylation system have been found to have anti-viral e...

Malhotra(Sunny),Bustamante(Marta F),Pérez-... PLoS One 2012-01-17

...HERC5, LY6E, RSAD2, SIGLEC1, and USP18. In vitro experiments in PBMC from healthy controls revealed specific induction o...

Shi(He-Xin),Yang(Kai),Liu(Xing),Liu(Xin-Yi... Mol Cell Biol 2010-06-02

...HERC5 could, respectively, enhance or impair IRF3-mediated gene expression. Mechanistically, HERC5 catalyzes the conjuga...

Zhao(Chen),Hsiang(Tien-Ying),Kuo(Rei-Lin),... Proc Natl Acad Sci U S A 2010-03-05

...Herc5, the major E3 ligase for ISG15 conjugation in human cells. These results establish a "loss of function" mechanism ...