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Replicated genetic evidence supports a role for HOMER2 in schizophrenia.

Gilks(William P),Allott(Emma H),Donohoe(Ga... Neurosci Lett 2010-04-06

...Homer2 is naturally truncated. We did not detect an allelic effect of rs2306428 on neuropsychological function nor on HO...

Interaction of Cupidin/Homer2 with two actin cytoskeletal regulators, Cdc42 s...

Shiraishi-Yamaguchi(Yoko),Sato(Yumi),Sakai... BMC Neurosci 2009-04-28

...Homer2 and two actin-cytoskeletal regulators, Cdc42 small GTPase and Drebrin.,Cupidin/Homer2 interacted with activated C...

Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional...

Cozzoli(Debra K),Goulding(Scott P),Zhang(P... J Neurosci 2009-08-03

...Homer2a/b expression and increased PI3K activity in this region. Virus-mediated knockdown of NAC Homer2b expression atte...

NFAT binding and regulation of T cell activation by the cytoplasmic scaffoldi...

Huang(Guo N),Huso(David L),Bouyain(Samuel)... Science 2008-02-06

...Homer2 and Homer3, members of the Homer family of cytoplasmic scaffolding proteins, are negative regulators of T cell ac...

Comparative proteomics and correlated signaling network of rat hippocampus in...

Liu(Xin-Yu),Yang(Jin-Liang),Chen(Li-Juan),... Proteomics 2008-05-02

...HOMER2), alpha-internexin (INA), and voltage-dependent anion channel 2 (VDAC2) were investigated by semiquantitative RT-...

Accumbens Homer2 overexpression facilitates alcohol-induced neuroplasticity i...

Szumlinski(Karen K),Ary(Alexis W),Lominac(... Neuropsychopharmacology 2008-08-07

...Homer2 protein levels that was apparent at 2 days, 2 weeks, and 2 months following withdrawal from alcohol drinking. The...

Homer2 and Homer3 interact with amyloid precursor protein and inhibit Abeta p...

Parisiadou(Loukia),Bethani(Ioanna),Michaki... Neurobiol Dis 2008-11-07

...Homer2 and Homer3 but not Homer1 proteins interact specifically with APP. Their expression inhibits APP processing and r...

Localization and expression of group I metabotropic glutamate receptors in th...

Kuwajima(Masaaki),Dehoff(Marlin H),Furuich... J Neurosci 2007-07-03

...Homer2 knock-out mice were used to assess the role of Homer in MPTP-induced redistribution of group I mGluRs. We also ex...

HOMER2 binds MYO18B and enhances its activity to suppress anchorage independe...

Ajima(Rieko),Kajiya(Keiko),Inoue(Takeshi),... Biochem Biophys Res Commun 2007-06-28

...HOMER2 enhanced the ability of MYO18B to suppress anchorage-independent growth. These results indicate that HOMER2 and M...

Homer proteins in Ca2+ signaling by excitable and non-excitable cells.

Worley(Paul F),Zeng(Weizhong),Huang(Guojin... Cell Calcium 2007-12-18

...Homer2 increases the GAP activity of RGS proteins and PLCbeta that accelerate the GTPase activity of Galpha subunits. Ho...

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