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[Neuroimmune mechanisms of lipocalin 2 in mediating chronic pain and itch].

Cui(XL),Sun(SY),Ma(JY),Zhou(GK),Liu(T) Sheng Li Xue Bao 2026-02-25

Lipocalin 2 (LCN2), a member of the lipocalin superfamily, is expressed and secreted by various cells and functions as a...

Endoplasmic Reticulum Stress in the Keratinocytes Contributes to Chronic Itch b…

Ge(W),Feng(Y),Zhang(L),Wang(QL),Zhang(CW),Wa… Neurosci Bull 2026-05-00

...LCN2) were significantly elevated in the affected skin under chronic itch conditions and in cultured keratinocyte HaCaT ...

Integrated DIA proteomics of tissue and exudate reveals screening markers for e…

Gong(Q),Wang(J),Ke(Q),Du(S),Huang(S),Zhu(T),… Clin Chim Acta 2026-08-05

...LCN2, and TNS1, were validated in serum samples using ELISA and receiver operating characteristic (ROC) curve analysis. ...

From tissue to blood: an integrated multi-omics signature identifies fibrogenes…

Ozcariz(E),Ostaszewski(M),Lopata(O),Ciglar(L… Front Immunol None

...LCN2 activity might play a relevant role in UC severity.

Integrated transcriptomic analysis of peripheral blood CD4 + T cells identifies…

Kou(H),Liu(H),Lai(L),Yang(S),Zhang(X),Sun(Y)… Immunol Res 2026-07-24

...LCN2. These genes exhibited significant correlations with immune-related pathways. In the validation cohorts, the four h...

Adipo-neuroinflammation, cognitive impairment and surrogate markers of cardiova…

Pacinella(G),Cuore(AD),Basso(MG),Casuccio(A)… Aging (Albany NY) 2026-07-23

...LCN2 levels. However, these relationships appear to be largely influenced by the underlying cardiometabolic profile. LCN...

The potential mechanism investigation of Lipocalin-2 in ferroptosis via the AMP…

Zhang(L),Zhao(A),Han(H),He(Y),Wang(Y),Gao(Q)… Int Immunopharmacol 2026-07-24

Sepsis-associated acute kidney injury (SA-AKI) is a common and severe complication of sepsis. Lipocalin-2 (LCN2), a biom...

Synovial fluid Lipocalin-2 as a biomarker for chronic prosthetic joint infectio…

Alías(A),Fernández-Valencia(JA),Martínez-Pas… Rev Esp Cir Ortop Traumatol None

...LCN2 levels. Synovial fluid LCN2 is a promising biomarker for the diagnosis of chronic PJI, especially in cases initiall...

Microbial metabolite Enterobactin impairs mitochondrial respiration and allevia…

Kushwaha(V),Yeoh(BS),Saha(P),Chassaing(B),Jo… Gut Microbes 2026-12-31

...Lcn2, which sequesters Ent) on mitochondrial function. We also examine the effects of the 2, 3-dihydroxybenzoic acid (2,...

SLC25A30 Regulates Mitochondrial Autophagy Through the PINK1/PARKIN Signaling P…

Xu(M),Wang(Y),Lv(W),Ding(Y),Liu(J),Diao(R),M… DNA Cell Biol 2026-07-00

...LCN2 (r = -0.98). SLC25A30 was significantly downregulated in SA-AKI rat renal tissues and LPS-induced HK-2 cells, accom...

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