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Natriuretic peptide precursor C delays meiotic resumption and sustains gap junc…

Franciosi(Federica),Coticchio(Giovanni),Lodd… Biol Reprod 2015-05-22

...NPPC) as a nonpharmacologic meiosis-arresting agent during IVM in a monoovulatory species. NPPC has been shown to mainta...

Multiple pathways mediate luteinizing hormone regulation of cGMP signaling in t…

Liu(Xueqing),Xie(Fang),Zamah(Alberuni Musa),… Biol Reprod 2015-02-20

...Nppc]) mRNA accumulation in vivo and in vitro. However, the cGMP downregulation precedes the decrease in Nppc mRNA by mo...

Blood pressure and urinary sodium excretion in relation to 16 genetic polymorph…

Hu(Bang-Chuan),Li(Yan),Liu(Ming),Li(Li-Hua),… Endocr J 2015-01-23

...NPPC, NPRA, NPRC, and Corin genes) and blood pressure in a Chinese population. The study population was recruited from a...

Protective effects of C-type natriuretic peptide on linear growth and articular…

Bükülmez(Hülya),Khan(Fozia),Bartels(Cynthia … Arthritis Rheumatol 2014-03-18

...NPPC) in chondrocytes. We introduced the CNP transgene into mice with experimental systemic inflammatory arthritis (K/Bx...

Identification and functional characterization of two novel NPR2 mutations in J…

Amano(Naoko),Mukai(Tokuo),Ito(Yoshiya),Narum… J Clin Endocrinol Metab 2014-06-03

...NPPC were sequenced, and the identified variants were characterized in vitro.,In two subjects, we identified two novel h...

CNP/NPR2 signaling maintains oocyte meiotic arrest in early antral follicles an…

Tsuji(Takehito),Kiyosu(Chiyo),Akiyama(Kouyou… Mol Reprod Dev 2013-06-19

...Nppc and Npr2, respectively encoding CNP and NPR2, in the ovaries of immature mice. Nppc and Npr2 mRNA were specifically...

Epidermal growth factor receptor signaling-dependent calcium elevation in cumul…

Wang(Yakun),Kong(Nana),Li(Na),Hao(Xiaoqiong)… Endocrinology 2013-11-12

...NPPC) and its receptor natriuretic peptide receptor 2 (NPR2). LH treatment results in the decrease of NPR2 guanylyl cycl...

Studies on the active sites ofBacillus cereus sphingomyelinase substitution of …

Ikezawa(H),Tameishi(K),Yamada(A),Tamura(H),T… Amino Acids 2013-11-04

...NPPC was comparable to that of the wild-type, while D156G catalyzed the hydrolysis of HNP andp-NPPC more efficiently tha...

Molecular control of oocyte meiotic arrest and resumption.

Liu(Lei),Kong(Nana),Xia(Guoliang),Zhang(Meij… Reprod Fertil Dev 2013-09-16

...NPPC), acting via its cognate receptor NPR2, increases cGMP levels in granulosa cells; the cGMP then diffuses into oocyt...

Hormonal coordination of natriuretic peptide type C and natriuretic peptide rec…

Lee(Kyung-Bon),Zhang(Meijia),Sugiura(Koji),W… Biol Reprod 2013-08-12

...Nppc expression. In this system, expression of Nppc mRNA was increased by estradiol (E2), with augmentation by follicle-...

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