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Targeted therapy in the treatment of lung cancer in Iceland 2010-2023.

Tryggvadóttir(SÁ),Stefánsson(GV),Birgisson... Acta Oncol 2026-04-09

...RET proto-oncogene (RET), MET proto-oncogene (MET), and NTRK, which can influence the selection of targeted therapies an...

Real-world clinical responses to selpercatinib in RET M918T-mutant medullary ...

Ökten(IN),Baydaş(T) Discov Oncol 2026-04-09

...RET inhibition. RESULTS: All three patients possessed pathogenic RET M918T mutations. Case 1 also harbored a pathogenic ...

Synthetic budding morphogenesis by optogenetic receptor tyrosine kinase signa...

Prahl(LS),Canlla(R),Huang(AZ),Alber(DS),Sh... bioRxiv 2026-04-02

...RET. We first show pharmacological manipulation of RET signaling controls the extent of branching in mouse embryonic kid...

The clinical consequences of diagnostic delay in sporadic pediatric MEN2B: a ...

Liu(Y),Liu(X),Huang(M),Li(Y),Zhang(X),Li(X... Eur J Pediatr 2026-04-10

This study aimed to retrospectively analyze the clinical characteristics, tumor staging, surgical outcomes, and prognosi...

Visualized accurate determination of ultra-trace Hg2+ using aptamer-conjugate...

Wang(C),Pei(Y),Zhang(J),Li(C),Li(Y),Chen(S... J Hazard Mater 2026-05-15

...RET). Hg²⁺ binding induces stable T-Hg²⁺-T pair formation, selectively releasing RhB and restoring the quenched ECL sign...

Unveiling bast fiber production in Upper Paleolithic North China: Microfibers...

Liu(L),He(Y),Cohen(D),Chen(X),Shi(J),Song(... PLoS One None

...ret microfiber remains, drawing on microfossil remains, usewear traces, ethnographic observation, and experimental archa...

Metastatic Medullary Thyroid Carcinoma Without Identifiable Primary Tumor Wit...

Lee(E),Byun(J),Kim(M),Kim(JH),Park(JY),Par... J Clin Med 2026-04-04

...RET mutation was not identified. Despite vandetanib treatment, the disease progressed and the patient expired. Conclusio...

Identification of Actionable Gene Variants in Pulmonary Large-Cell Neuroendoc...

Szpechcinski(A),Pelc(M),Lechowicz(U),Szolk... Int J Mol Sci 2026-03-24

...retrospective cohort of LCNEC patients using a targeted NGS approach. Microscopic diagnosis was established according to...

Deciphering RTK-RAS and MAPK Pathway Dependencies in Gemcitabine-Treated Panc...

Diaz(FC),Waldrup(B),Carranza(FG),Manjarrez... Int J Mol Sci 2026-03-26

...RET mutations were significantly enriched in gemcitabine-treated tumors. Early-onset cases demonstrated differential enr...

Vitamin D Deficiency Activates Gdnf-Ret-pErk1/2 Signal and Induces Kidney Mal...

Yu(M),Ye(N),Ju(H),Miao(Q),Wang(C),Dai(R),C... Int J Mol Sci 2026-03-27

...reteric bud tissue revealed significantly increased activity of Gdnf-Ret-p-Erk1/2 signaling in the VDD group. In vivo in...

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