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RPN2 Gene Confers Osteosarcoma Cell Malignant Phenotypes and Determines Clinica…

Fujiwara(Tomohiro),Takahashi(Ryou-U),Kosaka(… Mol Ther Nucleic Acids 2014-09-03

...RPN2 expression in osteosarcoma. Immunohistochemical evaluation of 35 osteosarcoma patient biopsies revealed that RPN2 w...

Integrated analysis of genome-wide copy number alterations and gene expression …

Loo(Lenora W M),Tiirikainen(Maarit),Cheng(Io… Genes Chromosomes Cancer 2013-08-26

...RPN2, TH1L, and PRPF6) that were upregulated and demonstrated a significant linear correlation (P < 0.05) for gene dosag...

A genome-wide association study for primary open angle glaucoma and macular deg…

Scheetz(Todd E),Fingert(John H),Wang(Kai),Ku… PLoS One 2013-12-27

...RPN2). Linked monogenic loci for POAG and AMD were also evaluated for evidence of association, none of which were found ...

Pregnancy is associated with decreased cardiac proteasome activity and oxidativ…

Iorga(Andrea),Dewey(Shannamar),Partow-Navid(… PLoS One 2013-05-06

...RPN2 and RPT4 (subunits of 19 S), β2 and α7 (subunits of 20 S) as well as PA28α and β5i (protein only) were not signific...

Genomic alterations in breast cancer patients in betel quid and non betel quid …

Kaushal(Mishi),Mishra(Ashwani K),Sharma(Jaga… PLoS One 2013-02-12

...RPN2, EMR3, VAV1, NNAT and MUC16 etc were seen in NBQC. Common alterations (>30%) were seen in 27 regions. Three network...

Molecular architecture of the 26S proteasome holocomplex determined by an integ…

Lasker(Keren),Förster(Friedrich),Bohn(Stefan… Proc Natl Acad Sci U S A 2012-03-30

...Rpn2 is rigid, supporting the lid, while Rpn1 is conformationally variable, positioned at the periphery of the ATPase ri...

The 19S cap puzzle: a new jigsaw piece.

Huber(Eva M),Groll(Michael) Structure 2012-06-29

...Rpn2 and use electron microscopy to examine differences between Rpn2 and Rpn1.

The structure of the 26S proteasome subunit Rpn2 reveals its PC repeat domain a…

He(Jun),Kulkarni(Kiran),da Fonseca(Paula C A… Structure 2012-06-29

...Rpn2 function to engage ubiquitin receptors. Rpn1 and Rpn2 are characterized by eleven tandem copies of a 35-40 amino ac...

RPN2 expression predicts response to docetaxel in oesophageal squamous cell car…

Kurashige(J),Watanabe(M),Iwatsuki(M),Kinoshi… Br J Cancer 2012-12-11

...RPN2-positive and RPN2-negative groups. We also studied susceptibility of RPN2-suppressed ESCC cells to docetaxel.,The R...

Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome.

Rosenzweig(Rina),Bronner(Vered),Zhang(Daonin… J Biol Chem 2012-07-02

...Rpn2. Rpn13 binds directly to Rpn2. These intrinsic polyubiquitin receptors may compete with substrate shuttles for thei...

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