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Lenalidomide as a disease-modifying agent in patients with del(5q) myelodyspl...

Giagounidis(Aristoteles),Mufti(Ghulam J),F... Ann Hematol 2014-02-26

...RPS14, Cdc25C, and PP2A). As a result, the agent specifically targets del(5q) clones while also promoting erythropoiesis...

Myelodysplastic syndromes with 5q deletion: pathophysiology and role of lenal...

Gaballa(Mahmoud R),Besa(Emmanuel C) Ann Hematol 2014-05-29

...RPS14 haplodeficiency and P53 activation. Subsequent to P53 activation, erythroid cell apoptosis and ineffective erythro...

Deletion 5q MDS: molecular and therapeutic implications.

Komrokji(Rami S),Padron(Eric),Ebert(Benjam... Best Pract Res Clin Haemato... 2014-09-29

...RPS14 gene leads to activation of the p53 pathway and the macrocytic anemia characteristic of this disorder, and loss of...

Identification of reference genes for qRT-PCR in human lung squamous-cell car...

Zhan(Cheng),Zhang(Yongxing),Ma(Jun),Wang(L... Acta Biochim Biophys Sin (S... 2014-11-24

...RPS14) were stably and constitutively expressed at high levels in all the samples tested. ACTB, EEF1A1, FAU, RPS9, RPS11...

[Classification and clinical findings of myelodysplastic syndromes].

Tsuruda(Kazuto),Hasegawa(Hiroo),Fuchigami(... Rinsho Byori 2014-08-15

...RPS14, TET2, IDH1/2, SF3B1, ASXL1, RUNX1, TP53, EZH2, JAK2, and WT1 have been revealed to be important for the prognosis...

PP2A: The Achilles Heal in MDS with 5q Deletion.

Sallman(David A),Wei(Sheng),List(Alan) Front Oncol 2014-10-08

...RPS14) gene, which leads to MDM2 sequestration with consequent p53 activation and erythroid cell death. Since its approv...

Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stress.

Zhou(X),Hao(Q),Liao(J),Zhang(Q),Lu(H) Oncogene 2013-03-11

...RPS14-MDM2 binding was induced upon ribosomal stress caused by actinomycin D or mycophenolic acid. Overexpression of RPS...

Correlation of clinical response and response duration with miR-145 induction...

Venner(Christopher P),Woltosz(Joanna Wegrz... Haematologica 2013-11-26

...RPS14 were examined in del(5q) (n=10) and non-del(5q) (n=18) myelodysplastic syndrome patient samples. Significantly inc...

Extreme conservation of the psaA/psaB intercistronic spacer reveals a transla...

Peredo(Elena L),Les(Donald H),King(Ursula ... J Mol Evol 2013-05-07

...rps14 operon of land plant (embryophyte) chloroplasts, where the first two cistrons are separated by a spacer region to ...

SAGE analysis highlights the putative role of underexpression of ribosomal pr...

de Lima(Deison Soares),Martins(Clarissa Si... Eur J Endocrinol 2013-01-25

...RPS14, and RPS29 were validated by real-time PCR.,We report the first SAGE library from normal pituitary tissue and GH-s...

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