Li(Y),Lin(L),Zhang(W),Wang(Y),Shen(H),Guan(Y) Discov Oncol 2025-08-02

...RSPO3 can be potential therapeutic targets for meningiomas. This study provides evidence and explores the biological sig...

Singh(A),Akhtar(A),Shukla(P) ADMET DMPK 2025-00-00

...RSPO3-LGR4/5-β-catenin cascade, the CD47/YAP/TEAD4 signalling axis, and HAb18G/CD147, are briefly elaborated in the cont...

Horikoshi(Momoko),Mӓgi(Reedik),van de Bunt... PLoS Genet 2016-04-27

...RSPO3) and FG (GCK and G6PC2). The index variant for one association signal at the G6PC2 locus is a low-frequency coding...

Madan(Babita),Virshup(David M) Mol Cancer Ther 2016-02-01

...RSPO3 are surprisingly common and markedly increase Wnt/β-catenin signaling in response to secreted Wnts. These mutation...

Styrkarsdottir(Unnur),Thorleifsson(Gudmar)... Nat Commun 2016-06-09

...RSPO3, rs577721086 (freq. 6.8%), that associates with increased spine BMD (P=6.6 × 10(-10), β=0.14). Importantly, both v...

Scholz(Beate),Korn(Claudia),Wojtarowicz(Je... Dev Cell 2016-05-27

...RSPO3 function remain elusive. Inducible endothelial Rspo3 deletion (Rspo3-iECKO) resulted in perturbed developmental an...

Boone(Jonathan D),Arend(Rebecca C),Johnsto... Lab Invest 2016-05-27

...RSPO3, PORCN, WLS, AXIN2, and three previously characterized RSPO fusion transcripts were assessed using Taqman assays. ...

Storm(Elaine E),Durinck(Steffen),de Sousa ... Nature 2016-01-25

...RSPO3 in PTPRK-RSPO3-fusion-positive human tumour xenografts inhibits tumour growth and promotes differentiation. Notabl...

Kang(Eugene),Yousefi(Mitra),Gruenheid(Sama... PLoS One 2016-08-19

...Rspo3/RSPO3 was the most highly expressed R-spondin in both mouse and human colon. R-spondin expression was found to be ...

Hao(Huai-Xiang),Jiang(Xiaomo),Cong(Feng) Cancers (Basel) 2016-06-24

...RSPO3 have recently been identified in various cancers. Significantly, genetic alterations in RNF43/ZNRF3/RSPO2/RSPO3 ha...