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Suppressor of cytokine signalling-6 promotes neurite outgrowth via JAK2/STAT5...

Gupta(Sakshi),Mishra(Kanchan),Surolia(Avad... PLoS One 2012-04-02

...SOCS6 in neuritogenesis. In this study, we examined the role of SOCS6 in neurite outgrowth and neuronal cell signalling....

SOCS5 and SOCS6 have similar expression patterns in normal and cancer tissues...

Yoon(Sungpil),Yi(Young-Su),Kim(Sang Soo),K... Tumour Biol 2012-02-06

...SOCS6 expressions. In addition, mRNA and protein levels of SOCS6 were down-regulated in liver cancer tissues. The result...

Expression of SOCS1-7 and CIS mRNA in porcine tissues.

Delgado-Ortega(Mario),Melo(Sandrine),Meure... Vet Immunol Immunopathol 2012-03-09

...SOCS6, and CIS), small intestine (SOCS1, SOCS4, SOCS6, and CIS), spleen (SOCS2, SOCS3, SOCS5, SOCS7, and CIS), trachea (...

Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal t...

Kazi(Julhash U),Sun(Jianmin),Phung(Bengt),... J Biol Chem 2012-12-28

...SOCS6 and Flt3 and tyrosine phosphorylation of SOCS6. Phosphopeptide fishing indicated that SOCS6 binds directly to phos...

LNCaP prostate cancer cells with autocrine interleukin-6 expression are resis...

Ge(Dongxia),Gao(Allen C),Zhang(Qiuyang),Li... Prostate 2012-10-02

...SOCS6 were expressed at approximately the same levels. Using siRNA to knockdown SOCS7 and CIS expression in LNCaP-S17 ce...

Structural basis for c-KIT inhibition by the suppressor of cytokine signaling...

Zadjali(Fahad),Pike(Ashley C W),Vesterlund... J Biol Chem 2011-01-31

...SOCS6 substrate recognition. Our results show that the SH2 domain of SOCS6 is essential for its interaction with c-KIT p...

Pim3 negatively regulates glucose-stimulated insulin secretion.

Vlacich(Gregory),Nawijn(Martijn C),Webb(Ge... Islets 2011-05-16

...SOCS6 and SOCS6 levels were strongly reduced in Pim3-/- islets. Overexpression of SOCS6 inhibited glucose-induced ERK1/2...

Porphyromonas gingivalis induction of microRNA-203 expression controls suppre...

Moffatt(Catherine E),Lamont(Richard J) Infect Immun 2011-09-02

...SOCS6, were evaluated by qRT-PCR. SOCS3 and SOCS6 mRNA levels were reduced >5-fold and >2-fold, respectively, in P. ging...

SOCS6, down-regulated in gastric cancer, inhibits cell proliferation and colo...

Lai(Rai-Hua),Hsiao(Ya-Wen),Wang(Mei-Jung),... Cancer Lett 2010-02-22

...SOCS6 inactivation. Ectopic expression of SOCS6 suppressed cell growth and colony formation, in part through eliciting i...

Epithelial induction of porcine suppressor of cytokine signaling 2 (SOCS2) ge...

Bruel(Timothée),Guibon(Roseline),Melo(Sand... Dev Comp Immunol 2010-06-14

...SOCS6 encoding sequences. With more than 92% identity predicted porcine SOCS proteins are very similar to their human co...

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