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Small ubiquitin-like modifier 3-modified proteome regulated by brain ischemia...

Yang(Wei),Sheng(Huaxin),Thompson(J Will),Z... Stroke 2014-06-10

...SUMO3-modified proteome regulated by brain ischemia using a novel SUMO transgenic mouse.,To enable SUMO proteomics analy...

Targeted identification of SUMOylation sites in human proteins using affinity...

Lamoliatte(Frederic),Bonneil(Eric),Durette... Mol Cell Proteomics 2014-04-02

...SUMO3-modified Lys residues in target proteins, most of which were previously unknown. Interestingly, we identified mixe...

Multidomain sumoylation of the ecdysone receptor (EcR) from Drosophila melano...

Seliga(Justyna),Bielska(Katarzyna),Wieczor... J Steroid Biochem Mol Biol 2014-01-08

...SUMO3 modification. Our research revealed that EcR undergoes isoform-specific multisumoylation. The pattern of modificat...

Investigation of SUMO pathway genes in the etiology of nonsyndromic cleft lip...

Carta(Eloisa),Pauws(Erwin),Thomas(Anna C),... Birth Defects Res A Clin Mo... 2013-06-19

...SUMO3, as well as the E3 ligases PIAS1 and PIAS2, which are required for sumoylation. Variants were analyzed in a cohort...

Native structure protects SUMO proteins from aggregation into amyloid fibrils...

Sabate(Raimon),Espargaro(Alba),Graña-Monte... Biomacromolecules 2013-02-12

...SUMO3 proteins are at risk of aggregation into amyloid structures if their native conformation is perturbed. Aggregation...

Alternative sumoylation sites in the Drosophila nuclear receptor Usp.

Bielska(Katarzyna),Seliga(Justyna),Wieczor... J Steroid Biochem Mol Biol 2013-01-10

...SUMO3 modification. Mutagenesis studies on the fragments of Usp indicated that sumoylation can occur alternatively on se...

Sumoylation in gene regulation, human disease, and therapeutic action.

Yang(Xiang-Jiao),Chiang(Cheng-Ming) F1000Prime Rep 2013-11-25

...SUMO3, as well as their homologues in various species. In this short review, we will discuss some recent examples to hig...

Development of a high-throughput screening assay for inhibitors of small ubiq...

Yang(Wei),Wang(Liangli),Paschen(Wulf) J Biomol Screen 2013-11-26

...SUMO3 as a SUMO protease substrate. A bacterial SUMOylation system was used to generate this substrate. A three-step pur...

Senp1 is essential for desumoylating Sumo1-modified proteins but dispensable ...

Sharma(Prashant),Yamada(Satoru),Lualdi(Mar... Cell Rep 2013-12-16

...Sumo3 (Sumo2/3), which can form poly-Sumo chains. However, a full understanding of Senp specificity in vivo is still lac...

Analysis of global sumoylation changes occurring during keratinocyte differen...

Heaton(Phillip R),Santos(Andres),Rosas-Aco... PLoS One 2012-06-04

...SUMO3 protein. The SNAP-tag allows covalent fluorescent labeling that is denaturation resistant. When combined with two-...

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