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Derivation of chondrocyte and osteoblast reporter mouse embryonic stem cell l...

Fu(Yu),Maye(Peter) Genesis 2015-10-06

...Col2a1)-ECFP, Bone Sialoprotein (BSP)-Topaz, and BSP-Topaz/Dentin Matrix Protein 1 (DMP1)-Cherry dual reporter mice. Col...

Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrody...

Cameron(T L),Gresshoff(I L),Bell(K M),Piró... Osteoarthritis Cartilage 2015-12-15

...Col2a1-Cre mice (Xbp1(CartΔEx2)), in which XBP1 activity is ablated specifically from cartilage, were analyzed histomorp...

Monotropein exerts protective effects against IL-1β-induced apoptosis and cat...

Wang(Feng),Wu(Longhuo),Li(Linfu),Chen(Siyi... Int Immunopharmacol 2015-07-28

...COL2A1 was increased. Taken together, these findings suggested that monotropein exerted anti-apoptosis and anti-cataboli...

Preparation of heparan sulfate-like polysaccharide and application in stem ce...

Zhao(Shancheng),Wang(Zhen),Chen(Jingxiao),... Carbohydr Res 2015-09-04

...COL2A1 was significantly upregulated in cells treated with the N,O-sulfated K5 polysaccharide confirming that the sulfat...

Effect of parathyroid hormone on early chondrogenic differentiation from mese...

Zhang(Yun),Kumagai(Ken),Saito(Tomoyuki) J Orthop Surg Res 2015-11-17

...Col2a1), collagen type X α1 chain, collagen type I α1 chain, SRY-box9 (Sox9), and type 1 PTH/PTHrP receptor (PTH1R) were...

A genetic pedigree analysis to identify gene mutations involved in femoral he...

Wang(Lin),Pan(Hehai),Zhu(Zhen-An) Mol Med Rep 2015-05-22

...COL2A1 gene of the proband; the clinical manifestations of the proband meet the criteria for osteonecrosis. The exons of...

Association of reduced type IX collagen gene expression in human osteoarthrit...

Imagawa(Kei),de Andrés(María C),Hashimoto(... Arthritis Rheumatol 2015-02-10

...COL2A1 enhancer and COL9A1 promoter.,Expression levels were determined using quantitative reverse transcription-polymera...

Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the incr...

Yoshida(Carolina Andrea),Kawane(Tetsuya),M... J Biol Chem 2015-02-02

...Col2a1 promoter-enhancer. Galnt3(-/-) mice showed a delay in endochondral ossification and shortened limbs at embryonic ...

Identification of a novel COL2A1 mutation (c.1744G>A) in a Japanese family: a...

Kishiya(Masaki),Nakamura(Yoshihide),Ohishi... J Med Case Rep 2015-05-15

...COL2A1) have been found to affect the entire skeletal system. Recently, inheritable skeletal dysplasia caused by novel C...

Analyses on the mechanisms that underlie the chondroprotective properties of ...

Greco(Karin V),Nalesso(Giovanna),Kaneva(Ma... Biochem Pharmacol 2015-04-28

...COL2A1 and NFAT transcription factors.,CT (10(-10)-10(-8)nM) induced significant up-regulation of cartilage phenotypic m...

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